NCHU Course Outline
Course Name (中) 高等基因體學與應用(8292)
(Eng.) Advanced Genomics and Applications
Offering Dept International Doctoral Program in Agriculture
Course Type Elective Credits 3 Teacher Shuen-Fang Lo
Department International Doctoral Program in AgriculturePh.D Language English Semester 2024-FALL
Course Description 後基因體世代提供充足之分子基因訊息,充分了解基因功能、調節機制、基因產物所引起之基本生化及生理反應等原理,並結合生物技術的方法,以探討參與生物生長、發育、逆境反應與代謝過程中所有相關基因群的表現、調控及其功能。可進而應用於作物在質及量上的改良、分子農場之應用等。
The post-genome generation provides sufficient molecular gene information, fully understands the gene function, regulatory mechanism, and basic biochemical and physiological reactions caused by gene products, and combines biotechnology methods to explore the participation in organism growth, regulation and function of all relevant gene family in development, stress response and metabolism. It can be further applied to the improvement of crop quality and quantity, and the application of molecular farming.
Prerequisites
self-directed learning in the course N
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
充分了解基因功能、調節機制、基因產物所引起之基本生化及生理反應等,並可進而應用於作物在質及量上的改良。
Fully understand the gene function, regulatory mechanism, and basic biochemical and physiological reactions caused by gene products, which can be applied to the improvement of crop quality and quantity.
topic Discussion/Production
Discussion
Lecturing
Attendance
Oral Presentation
Assignment
Quiz
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 The basic unit of life.
Week 2 The genetic code.
Week 3 Structural genomics, Comparative genomics, and Functional genomics.
Week 4 Transcriptomics.
Week 5 Epigenetics and Epigenome profiling.
Week 6 Multi-Omics and genomics and Proteomics.
Week 7 Genotyping and Phenotyping vs Forward and Reverse genetics approach
Week 8 Midterm Exam
Week 9 Mutagenesis– RNA interferences, chemical and physical mutagenesis, insertional mutagenesis, CRISPR/Cas9, VIGS
Week 10 Meta-analysis
Week 11 Utilization of Bioinformatics.
Week 12 Tools to accelerate gene functional analysis and synthetic biology
Week 13 Next-Generation Omics Technologies
Week 14 Genome projects
Week 15 Evolution, biology, and sustainable application
Week 16 Latest research and review of Genomics
Week 17 Application and Biotechnology of genomics.
Week 18 Final Exam
Evaluation
Written examination (middle and final), Group discussion
Textbook & other References
1.Leland Hartwell, Michael Goldberg, Janice Fischer, Leroy Hood. (2020) Genetics: From Genes to Genomes 7th. McGraw-Hill Higher Education.
2.Jocelyn E. Krebs, Elliott S. Goldstein, Stephen T. Kilpatrick (2017) Lewin’s GENES XII 12th. Jones & Bartlett Learning.
3.Alonso, J. M. and Stepanova, A. N. (2015) Plant functional genomics - methods and protocols. Humana press.
4.Spillane, C. and Mckeown, P. C. (2014) Plant epigenetics and epigenomics – methods and protocols. Humana press.
Teaching Aids & Teacher's Website
Lecture media
Office Hours
Monday 16:00~17:00
Sustainable Development Goals, SDGs
 include experience courses:N
Please respect the intellectual property rights and use the materials legally.Please repsect gender equality.
Update Date, year/month/day:None Printed Date, year/month/day:2024 / 10 / 11
The second-hand book website:http://www.myub.com.tw/