NCHU Course Outline
Course Name (中) 細胞訊息傳導特論(9109)
(Eng.) Special Topics on Cellular Signal Transduction
Offering Dept Graduate Institute of Veterinary Pathobiology
Course Type Elective Credits 2 Teacher HSUAN,SHIH-LING
Department Graduate Institute of Veterinary PathobiologyPh.D Language 中/英文 Semester 2024-FALL
Course Description 介紹炎症反應、傳染病相關重要訊息傳導路徑;藉由文獻研讀、討論與口頭報告,瞭解訊息傳導研究之實驗策略及近期發展。
This course will introduce the signal transduction pathways and their regulation mechanisms involved in inflammatory response and in infectious disease.


Prerequisites 細胞訊息傳導與調控 self-directed learning in the course N
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
使學生瞭解炎症反應及傳染病相關訊息傳導路徑及調控機制。
This course will provide students the knowledge of signal transduction pathways and regulation mechanisms in inflammatory response and in infectious disease.

1.Logical thinking, analytical reasoning, questioning and application of communication skills
4.Logical thinking and the ability of the experimental results of the judgments
5.Ability of Independent thinking and innovative research
60
20
20
Lecturing
Discussion
Oral Presentation
Written Presentation
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 Pattern recognition receptor (PRR) signaling- Overview
Week 2 PRR signaling- Toll-like receptors (TLRs) I
Week 3 PRR signaling- Toll-like receptors (TLRs) II
Week 4 PRR signaling- C-type lectin receptors (CLRs)
Week 5 PRR signaling- Retinoic acid-inducible gene (RIG)-I-like receptors (RLRs)
Week 6 PRR signaling- NOD-like receptors (NLRs) I
Week 7 PRR signaling- NOD-like receptors (NLRs) II
Week 8 PRRs and pathogens
Week 9 Literature discussion
Week 10 Cell death- Apoptosis: intrinsic and extrinsic pathways
Week 11 Cell death- Apoptosis: ER stress
Week 12 Cell death- Pyroptosis
Week 13 Cell death- Autophagy and more
Week 14 Integrin signaling
Week 15 Signal transduction in infectious disease I
Week 16 Signal transduction in infectious disease II
Week 17 Literature discussion
Week 18 Student presentation
Evaluation
口頭與書面報告
Oral presentation and written report

Textbook & other References
1. Guide to Signal Pathways in Immune Cells, 2009, E. N. Wardle, Human Press.
2. Integrins, 2007, D. A. Cheresh, Elsevier
3. Structure and Function in Cell Signaling, 2008, J. Nelson, John Wiley & Sons.
4. Journal Articles.



Teaching Aids & Teacher's Website
iLearning


Office Hours
Friday, 2:00 - 3:00 PM or by appointment


Sustainable Development Goals, SDGs
 include experience courses:N
Please respect the intellectual property rights and use the materials legally.Please repsect gender equality.
Update Date, year/month/day:None Printed Date, year/month/day:2024 / 10 / 11
The second-hand book website:http://www.myub.com.tw/