NCHU Course Outline
Course Name (中) 生物有機化學(6884)
(Eng.) Bio-Organic Chemistry
Offering Dept Graduate Institute of Biomedical Engineering
Course Type Elective Credits 3 Teacher Chian-Hui Lai
Department Graduate Institute of Biomedical Engineering/Graduate Language English Semester 2024-FALL
Course Description Introduction of organic chemistry concepts and applying them to construct new bio-releative materials. Classes include lectures and discussions.
(1) Amino acids, peptides, proteins and their biochemical and physical properties. (2) The synthesis of their derivatives, combinatorial chemistry, protein modification and the application of chemical synthetic enzymes. (3) Carbohydrates and biochemical properties. (4) Chemistry Chemical and oligosaccharide/polysaccharide chemical synthesis. (5) Spectroscopic identification of chemical structure.
Prerequisites
self-directed learning in the course N
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
To have basic organic chemistry concepts and apply them to chemical modification of biomedical materials.
Provide a basic understanding of the chemical properties of biomolecules and biomacromolecules. Students will learn about biological molecules such as amino acids, proteins, carbohydrates and fats. Another focus will be on biophysical properties, synthesis and modification.
1.Possess professional knowledge in biomedical engineering.
2.Plan and implement research projects, and have the ability to solve problems independently.
3.Ability to write scientific papers and communicate research results effectively.
4.Integration in interdisciplinary research and innovative research skills.
5.Possess insightful perspective on industry and globalization.
6.Capability of leadership, management, planning, communication and lifelong learning.
25
10
10
25
25
5
Lecturing
Discussion
topic Discussion/Production
Quiz
Assignment
Oral Presentation
Attendance
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 第一周 Introduction of bio-organic chemistry and organic chemistry
Week 2 第二周 structure and bonding, covalent bond

Week 3 第三周 Concept of isomers
Week 4 第四周 DNA structure and its function I
Week 5 第五周 DNA structure and its function II
Week 6 第六周 Proteins Structure & Function I: Amino Acids, Peptides and Proteins
Week 7 第七周 Proteins Structure & Function II: Chemical Peptide Synthesis
Week 8 第八周 Protein/peptide modification
Week 9 第九周 Mid Exam
Week 10 第十周 Enzymes: Biological Catalysts I:
Week 11 第十一周 Enzymes: Biological Catalysts II: Enzymes in Chemical Synthesis
Week 12 第十二周 Carbohydrate Chemistry (Saccharide Chemistry) and its function
Week 13 第十三周 Chemical synthesis of oligosaccharides and carbohydrates
Week 14 第十四周 Lipids & Biological Membranes Transport
Week 15 第十五周 Tools in Biochemistry I: Structure Determination: Mass spectrometery, Infrared spectroscopy and NMR
Week 16 第十六周 Tools in Biochemistry II : Concepts and techniques of using electrophoresis, ELISA, PCR
Week 17 第十七周 Health problems associated with biochemistry
Week 18 第十八周 Final Exam
Evaluation
隨堂表現 20%,期中考40%,期末考 20%,報告 20%
Textbook & other References
書名 Bioorganic chemistry : highlights and new aspects. 作者Diederichsen, Ulf (EDT)/ Lindh書局Wiley-VCH, 出版:1999

書名 Organic chemistry, 9th Edition 作者 John McMurry 書局 CENGAGE Learning, 出版:2015
Teaching Aids & Teacher's Website
Web: http://www.bme.nchu.edu.tw/member.php?id=1
Email: chianhuilai@dragon.nchu.edu.tw
Office Hours
星期二: 17:00~18:00
Sustainable Development Goals, SDGs
01.No Poverty   03.Good Health and Well-Being   04.Quality Education   05.Gender Equality   06.Clean Water and Sanitation   09.Industry, Innovation and Infrastructure   12.Responsible Consumptioninclude experience courses:N
Please respect the intellectual property rights and use the materials legally.Please repsect gender equality.
Update Date, year/month/day:None Printed Date, year/month/day:2024 / 10 / 13
The second-hand book website:http://www.myub.com.tw/