NCHU Course Outline
Course Name (中) 動物病毒學文獻探討(二)(7165)
(Eng.) Review of Literature in Animal Virology(II)
Offering Dept Department of Veterinary Medicine
Course Type Elective Credits 1 Teacher CHI-YOUNG WANG ect.
Department Graduate Institute of Microbiology and Public Health/Graduate Language English Semester 2024-FALL
Course Description This class is to design as a open discussion for the graduate students who are interested to further acquire more knowledge in the field of molecular virology. Students can learn how to evaluate, interpret, and complete a scientific research proposal.
Prerequisites
self-directed learning in the course N
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
Establishment of the basic reading ability for the graduate student.
Training of the scientific logic for the graduate student.
Understanding of the experiment techniques in the molecular virology.
1.Professional knowledge in microbiology and public health.
2.Ability to conduct experiments in microbiology, public health, biochemistry and molecular biology.
3.Ability to read research articles in English or Chinese.
4.Ability of logical thinking and lifelong learning.
30
20
20
30
Discussion
Oral Presentation
Attendance
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 Characterization of the DNA binding activity of structural protein VP1 from chicken anemia virus. BMC Veterinary Research 14:155.
Week 2 Interferon-induced human MxA GTPase blocks nuclear import of Thogoto virus nucelocapsids. Proc. Natl. Acad. Sci. USA 96:2082-2086.
Week 3 Inhibition of Borna disease virus replication by an endogenous bornavirus-like element in the ground squirrel genome. Proc. Natl. Acad. Sci. 36:13175-13180.
Week 4 Student report:I
Week 5 Importin alpha nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein. Journal of Biological Chemistry 278:28193-28200.
Week 6 Entry of Scotophilus bat coronavirus-512 and severe acute respiratory syndrome coronavirus in human and multiple animal cells. Pathogens 8:259.
Week 7 Infectious bronchitis virus regulates cellular stress granule signaling. Viruses 12:536.
Week 8 In vivo siRNA delivery using JC virus-like particles decreases the expression of RANKL in rats. Molecular Therapy-Nucleic Acids 5:e298.
Week 9 Student report:II
Week 10 Characterization of the DNA binding properties of polyomavirus capsid proteins. Journal of Virology 67:6327-6331.
Week 11 Functional analysis of the interferon-stimulated response element of porcine circovirus type 2 and its role during viral replication in vitro and in vivo. Virology Journal 9:152.
Week 12 Encephalomyocarditid virus viroporin 2B activates NLRP3 inflammasome. Plos Pathogens 8:e1002857.
Week 13 Cellular transcription factor SP1 recruits simian virus 40 capisd proteins to the viral package signal, ses. Journal of Virology 76:5915-5924.
Week 14 Interaction of the replication proteins and the capsid protein of porcine circovirus type 1 and 2 with host proteins. Virology 386:122-131.
Week 15 Student report:III
Week 16 HIV-1 myristoylated Nef treatment of murine microglial cells activates inducible nitric oxide synthase, NO2 production and neurotoxic activity. Plos One 10:e0130189.
Week 17 Efficient gene transfer using the human JC virus-like particle that inhibits human colon adenocarcinoma growth in anude mouse model. Gene Theray 17:1033-1041
Week 18 Final discussion
Evaluation
The performance of report and discussion
Textbook & other References
Journal of Virology
Journal of General Virology
Plos Pathogens
Molecular therapy
Pathogens
Journal of Biological Chemistry
Virology
Plos One
Teaching Aids & Teacher's Website

Office Hours
Friday 4:00 PM-5:00 PM
Sustainable Development Goals, SDGs
 include experience courses:N
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Update Date, year/month/day:None Printed Date, year/month/day:2024 / 10 / 07
The second-hand book website:http://www.myub.com.tw/