NCHU Course Outline |
Course Name | (中) 禽鳥胚胎實驗動物(6582) | ||||
(Eng.) Avian Embryos as Model Animal | |||||
Offering Dept | Department of Life Sciences | ||||
Course Type | Elective | Credits | 2 | Teacher | CHENG, HSU-CHEN |
Department | Department of Life Sciences/Graduate | Language | English | Semester | 2024-FALL |
Course Description | 介紹禽鳥胚胎發育的過程與特色,一般使用實驗動物的需求與條件,設計動物實驗須注意的事項,動物實驗結果蒐集與分析。 | ||||
Prerequisites | self-directed learning in the course | Y |
Relevance of Course Objectives and Core Learning Outcomes(%) | Teaching and Assessment Methods for Course Objectives | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Course Objectives | Competency Indicators | Ratio(%) | Teaching Methods | Assessment Methods | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1. 培養學生能使用禽鳥胚胎作為實驗動物並獨立設計實驗的能力 |
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50 % Class discussion, 50% laboratory experiment | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Textbook & other References | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
10/7 Genomic Organization and Expression of the Doublesex-Related Gene Cluster in Vertebrates and Detection of Putative Regulatory Regions for DMRT1. GENOMICS Vol. 77, Numbers 1–2, September 2001 Expression profiling of purified mouse gonadal somatic cells during the critical time window of sex determination reveals novel candidate genes for human sexual dysgenesis syndromes. Human Molecular Genetics, 2006, Vol. 15, No. 3 417–431 Expression of Dmrt1 in the Genital Ridge of Mouse and Chicken Embryos Suggests a Role in Vertebrate Sexual Development. Developmental Biology 215, 208–220 (1999) 10/14 Cytochrome P450 aromatase expression in human seminoma Reproductive Biology and Endocrinology 2005, 3:72 Effect of luteinising-hormone in vivo on ovarian cell subpopulations of newly-hatched chicks. British Poultry Sciencde (2000) 41: 494–501 Onset of meiosis in the chicken embryo; evidence of a role for retinoic acid. BMC Developmental Biology 2008, 8:85 Germ Cell-Intrinsic and -Extrinsic Factors Govern Meiotic Initiation in Mouse Embryos. Science 322, 1685-87 (2008); Retinoic acid regulates sex-specific timing of meiotic initiation in mice. 2474–2479 _ PNAS _ February 21, 2006 _ vol. 103 _ no. 8 Approaches to define the role of SF-1 at different levels of the hypothalamic-pituitary-steroidogenic organ axis. Molecular and Cellular Endocrinology 179 (2001) 33–37 10/21 Proteome Analysis of Chicken Embryonic Gonads: Identification of Major Proteins From Cultured Gonadal Primordial Germ Cells. MOLECULAR REPRODUCTION AND DEVELOPMENT 72:521–529 (2005) Using real time RT-PCR analysis to determine multiple gene expression patterns during XX and XY mouse fetal gonad development. Gene Expression Patterns 5 (2004) 141–149 Profiles of mRNA Expression of Genes Related to Sex Differentiation of the Gonads in the Chicken Embryo. 2003 Poultry Science 82:1462–1467 Sex Differentiation and mRNAExpression of P450c17, P450arom andAMH in Gonads of the Chicken. MOLECULAR REPRODUCTION AND DEVELOPMENT 55:20–30 (2000) Sexually dimorphic gene expression in the developing mouse gonad. Gene Expression Patterns 2 (2002) 359–367 The unique genomic properties of sex-biased genes: Insights from avian microarray data. BMC Genomics 2008, 9:148 Sexually dimorphic gene expression in the chick brain before gonadal differentiation. 2009 Poultry Science 88 :1003–1015 10/28 Differentiation of Female Primordial Germ Cells in the Male Testes of Chicken. MOLECULAR REPRODUCTION AND DEVELOPMENT 74:68–75 (2007) Five Azacytidine, A DNA Methyltransferase Inhibitor, Specifically Inhibits Testicular Cord Formation and Sertoli Cell Differentiation In Vitro. MOLECULAR REPRODUCTION AND DEVELOPMENT Embryonic Testis Cord Formation and Mesonephric Cell Migration Requires the Phosphotidylinositol 3-Kinase Signaling Pathway. BIOLOGY OF REPRODUCTION 67, 1927–1935 (2002) The Partial Female to Male Sex Reversal in Wnt-4- Deficient Females Involves Induced Expression of Testosterone Biosynthetic Genes and Testosterone Production, and Depends on Androgen Action. Endocrinology 146(9):4016–4023 11/4 Cell proliferation is necessary for the determination of male fate in the gonad. Developmental Biology 258 (2003) 264–276 Effects of FGF9 on embryonic Sertoli cell proliferation and testicular cord formation in the mouse. Int. J. Dev. Biol. 48: 637-643 (2004) Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos. Developmental Biology 280 (2005) 150–161 Stabilization of b-catenin in XY gonads causes male-to-female sex-reversal. Human Molecular Genetics, 2008, Vol. 17, No. 19 2949 – 2955 Genetic programs that regulate testicular and ovarian development. Molecular and Cellular Endocrinology 265–266 (2007) 3–9 11/11 Homograft Implants of Young Testes, Ovaries and Ovotestes in the Intact Female Chick. J. Embryol. exp. Morph., Vol. 11, Part 4, pp. 637-648, December 1963 Heterotopic Transplantation of Testes in Newly Hatched Chickens and Subsequent Production of Offspring via Intramagnal Insemination. BIOLOGY OF REPRODUCTION 76, 598–603 (2007) Mechanisms of gonadal morphogenesis are not conserved between chick and mouse. Developmental Biology 302 (2007) 132–142 Specification of germ layer identity in the chick gastrula. BMC Developmental Biology 2007, 7:91 |
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Update Date, year/month/day:None | Printed Date, year/month/day:2024 / 10 / 11 |
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