NCHU Course Outline
Course Name (中) 電腦輔助蛋白質結構解析特論(一)(6075)
(Eng.) Special Lectures on Computer-aided Protein Structur1e Determination(I)
Offering Dept Graduate Institute of Genomics and Bioinformatics
Course Type Elective Credits 2 Teacher Jyung-Hurng Liu
Department Graduate Institute of Genomics and Bioinformatics/Graduate Language 中/英文 Semester 2024-FALL
Course Description 使學生了解電腦程式在輔助蛋白質晶體結構解析上之應用並熟悉相關程式操作,本課程將向學生介紹當今蛋白質晶體結構解析之相關電腦程式,並讓學生實際操作練習。

Prerequisites
self-directed learning in the course N
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
1. 使學生了解電腦程式在輔助蛋白質晶體結構解析上之應用2. 熟悉蛋白質晶體結構解析相關程式操作

1.
3.
4.
45
45
10
Lecturing
Attendance
Assignment
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 Introduction
Week 2 Introduction to Protein Structure Determination
Week 3 Introduction to X-ray Crystallography (I)
Week 4 Introduction to X-ray Crystallography (II)
Week 5 Introduction to X-ray Crystallography (III)
Week 6 X-ray Diffraction Data Collection (I)
Week 7 X-ray Diffraction Data Collection (II)
Week 8 X-ray Diffraction Data Collection (III)
Week 9 Midterm Exam
Week 10 MAD and MIR Data Collection (I)
Week 11 MAD and MIR Data Collection (II)
Week 12 MAD and MIR Data Collection (III)
Week 13 MAD and MIR Data Collection (IV)
Week 14 Molecular Replacement Method (I)
Week 15 Molecular Replacement Method (II)
Week 16 Molecular Replacement Method (III)
Week 17 Molecular Replacement Method (IV)
Week 18 Final Exam
Evaluation
Attendance(30%), Homework(70%)

Textbook & other References
Crystallography Made Crystal Clear: A Guide for Users of Macromolecular Models, 3rd, 2006.
Publisher: Academic Press
Author: Gale Rhodes
ISBN: 9780125870733
Teaching Aids & Teacher's Website
iLearning
Office Hours
3-4PM, Thr (Appointment by email)
Sustainable Development Goals, SDGs
04.Quality Education   09.Industry, Innovation and Infrastructure   17.Partnerships for the Goalsinclude experience courses:N
Please respect the intellectual property rights and use the materials legally.Please repsect gender equality.
Update Date, year/month/day:None Printed Date, year/month/day:2024 / 10 / 11
The second-hand book website:http://www.myub.com.tw/