| Course Name |
(中) 高等基因體學與應用(8292) |
| (Eng.) Advanced Genomics and Applications |
| Offering Dept |
International Doctoral Program in Agriculture |
| Course Type |
Elective |
Credits |
3 |
Teacher |
Shuen-Fang Lo |
| Department |
International Doctoral Program in AgriculturePh.D |
Language |
English |
Semester |
2024-FALL |
| Course Description |
後基因體世代提供充足之分子基因訊息，充分了解基因功能、調節機制、基因產物所引起之基本生化及生理反應等原理，並結合生物技術的方法，以探討參與生物生長、發育、逆境反應與代謝過程中所有相關基因群的表現、調控及其功能。可進而應用於作物在質及量上的改良、分子農場之應用等。
The post-genome generation provides sufficient molecular gene information, fully understands the gene function, regulatory mechanism, and basic biochemical and physiological reactions caused by gene products, and combines biotechnology methods to explore the participation in organism growth, regulation and function of all relevant gene family in development, stress response and metabolism. It can be further applied to the improvement of crop quality and quantity, and the application of molecular farming. |
| Prerequisites |
|
self-directed learning in the course |
N |
| Relevance of Course Objectives and Core Learning Outcomes(%) |
Teaching and Assessment Methods for Course Objectives |
| Course Objectives |
Competency Indicators |
Ratio(%) |
Teaching Methods |
Assessment Methods |
充分了解基因功能、調節機制、基因產物所引起之基本生化及生理反應等，並可進而應用於作物在質及量上的改良。
Fully understand the gene function, regulatory mechanism, and basic biochemical and physiological reactions caused by gene products, which can be applied to the improvement of crop quality and quantity. |
|
|
| topic Discussion/Production |
| Discussion |
| Lecturing |
|
| Attendance |
| Oral Presentation |
| Assignment |
| Quiz |
|
| Course Content and Homework/Schedule/Tests Schedule |
| Week |
Course Content |
| Week 1 |
The basic unit of life. |
| Week 2 |
The genetic code. |
| Week 3 |
Structural genomics, Comparative genomics, and Functional genomics. |
| Week 4 |
Transcriptomics. |
| Week 5 |
Epigenetics and Epigenome profiling. |
| Week 6 |
Multi-Omics and genomics and Proteomics.
|
| Week 7 |
Genotyping and Phenotyping vs Forward and Reverse genetics approach
|
| Week 8 |
Midterm Exam
|
| Week 9 |
Mutagenesis– RNA interferences, chemical and physical mutagenesis, insertional mutagenesis, CRISPR/Cas9, VIGS
|
| Week 10 |
Meta-analysis
|
| Week 11 |
Utilization of Bioinformatics.
|
| Week 12 |
Tools to accelerate gene functional analysis and synthetic biology
|
| Week 13 |
Next-Generation Omics Technologies
|
| Week 14 |
Genome projects
|
| Week 15 |
Evolution, biology, and sustainable application
|
| Week 16 |
Latest research and review of Genomics
|
| Week 17 |
Application and Biotechnology of genomics. |
| Week 18 |
Final Exam |
|
| Evaluation |
| Written examination (middle and final)， Group discussion |
| Textbook & other References |
1.Leland Hartwell, Michael Goldberg, Janice Fischer, Leroy Hood. (2020) Genetics: From Genes to Genomes 7th. McGraw-Hill Higher Education.
2.Jocelyn E. Krebs, Elliott S. Goldstein, Stephen T. Kilpatrick (2017) Lewin’s GENES XII 12th. Jones & Bartlett Learning.
3.Alonso, J. M. and Stepanova, A. N. (2015) Plant functional genomics - methods and protocols. Humana press.
4.Spillane, C. and Mckeown, P. C. (2014) Plant epigenetics and epigenomics – methods and protocols. Humana press. |
| Teaching Aids & Teacher's Website |
| Lecture media |
| Office Hours |
| Monday 16:00~17:00 |
| Sustainable Development Goals, SDGs |
| | include experience courses：N |
|