| Course Name |
(中) 族群遺傳與演化(8013) |
| (Eng.) Population genetics and evolution |
| Offering Dept |
Graduate Institute of Biotechnology |
| Course Type |
Elective |
Credits |
3 |
Teacher |
湯森林 |
| Department |
Graduate Institute of BiotechnologyPh.D |
Language |
English |
Semester |
2024-FALL |
| Course Description |
Population genetics is a discipline of genetics that study the mechanism of gene frequency changes through time in a population and among populations. It is the fundamental basis of biological evolution. It also has been widely applied to the field of medicine and agriculture. This course is aimed to introduce basic concept of population genetics from causes of gene frequency changes to molecular evolution and population genomics. This course should provide a solid base for other special topics in evolutionary biology and conservation, such as conservation genetics, molecular evolution, and evolutionary genomics.
This is a graduate level course intended for PhD students to learn the fundamentals of population genetics and evolution. The course will be primarily discussion and based on the chapter and paper reading assignments; on most days, there will be no lectures. Students are expected to complete all reading assignments ahead of each class and be prepared for critical discussion.
At the end of the course, we hope that this course will help students develop as independent scientists. Specifically, students will:
Learn how to critically read and evaluate scientific publications.
Identify interesting research questions and propose experimental tests in the form of a grant.
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| Prerequisites |
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self-directed learning in the course |
N |
| Relevance of Course Objectives and Core Learning Outcomes(%) |
Teaching and Assessment Methods for Course Objectives |
| Course Objectives |
Competency Indicators |
Ratio(%) |
Teaching Methods |
Assessment Methods |
| 知識整合與歸納能力的養成 |
| 1.Capable of Independently acquiring new knowledge about cutting-edge Biotechnology. |
| 2.Capable of verbally expressing ideas and conveying opinions. |
| 3.Capable of searching and retrieving data. |
| 4.Capable of planning and designing laboratory experiments. |
| 6.Capable of analyzing data and experimental results. |
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| Written Presentation |
| Quiz |
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| Course Content and Homework/Schedule/Tests Schedule |
| Week |
Course Content |
| Week 1 |
Week 1 Class organization/Introduction/Thinking like a population geneticist
Week 2 Genotype frequencies
Week 3 Genetic drift and effective population size
Week 4 Genetic drift and effective population size
Week 5 Population structure and gene flow
Week 6 Population structure and gene flow
Week 7 Mutation
Week 8 Natural selection
Week 9 Natural selection (midterm due)
Week 10 Molecular Evolution 1
Week 11 Clades/Trees
Week 12 Molecular Evolution 2
Week 13 Sexual selection
Week 14 Evo-Devo
Week 15 Speciation
Week 16 Cooperation and conflict (final exam [grant proposal] due)
Week 17 Coevolution
Week 18 Grant “reading committee”: Should grant be funded?
Revision of grant due
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| Evaluation |
每週作業30%
出席率 30%
期中報告15%
期末報告25%
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| Textbook & other References |
| Population Genetics, Matthew B. Hamilton (Wiley-Blackwell, 2009) |
| Teaching Aids & Teacher's Website |
| PPT slides |
| Office Hours |
| by appointment |
| Sustainable Development Goals, SDGs |
| | include experience courses：N |
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