| Relevance of Course Objectives and Core Learning Outcomes(%) |
Teaching and Assessment Methods for Course Objectives |
| Course Objectives |
Competency Indicators |
Ratio(%) |
Teaching Methods |
Assessment Methods |
| 使學生從分子3D結構層面去瞭解膜蛋白的功能，並利用這些訊息去應用在藥物開發及臨床診斷 |
|
|
| topic Discussion/Production |
| Discussion |
| Lecturing |
|
|
| Course Content and Homework/Schedule/Tests Schedule |
| Week |
Course Content |
| Week 1 |
Classification of membrane proteins
|
| Week 2 |
Membrane protein folding and insertion
|
| Week 3 |
Photoreaction center
|
| Week 4 |
Electron transport complex
|
| Week 5 |
Channels
|
| Week 6 |
Transporters
|
| Week 7 |
Receptors, G protein couple receptor (GPCR)
|
| Week 8 |
Mid-term exam |
| Week 9 |
Porin |
| Week 10 |
Membrane enzymes |
| Week 11 |
Pore-forming toxins |
| Week 12 |
Expression and purification of integral membrane protein |
| Week 13 |
Crystallization of integral membrane proteins
|
| Week 14 |
Functional studies of membrane proteins |
| Week 15 |
Structural studies of membrane proteins, Pharmaceutical applications |
| Week 16 |
Final exam |
| Week 17 |
Spontaneous learning |
| Week 18 |
Spontaneous learning |
|
| Evaluation |
期中個別報告：學生選定期刊論文來做專題討論
期末分組報告：由老師訂定一個計劃方向，由學生去搜索相關文獻，做綜合性的專題討論
|
| Textbook & other References |
Biophysical Analysis of Membrane Proteins: Investigating Structure and Function, Eva Pebay-Peyroula
Membrane Structural Biology: With Biochemical and Biophysical Foundations, Mary Luckey
Journal publications in Nature, Science, Nature Structural & Molecular Biology, EMBO, PNAS, Nature Protocol, Nature Methods, etc.
|
| Teaching Aids & Teacher's Website |
Biophysical Analysis of Membrane Proteins: Investigating Structure and Function, Eva Pebay-Peyroula
Membrane Structural Biology: With Biochemical and Biophysical Foundations, Mary Luckey
Journal publications in Nature, Science, Nature Structural & Molecular Biology, EMBO, PNAS, Nature Protocol, Nature Methods, etc. |
| Office Hours |
| Every Tuesday 9:00-12:00 AM. |
| Sustainable Development Goals, SDGs |
| 11.Sustainable Cities and Communities | include experience courses：N |
|