| Relevance of Course Objectives and Core Learning Outcomes(%) |
Teaching and Assessment Methods for Course Objectives |
| Course Objectives |
Competency Indicators |
Ratio(%) |
Teaching Methods |
Assessment Methods |
| 知識整合與歸納能力的養成 |
| 3.Capable of searching and retrieving data. |
| 4.Capable of planning and designing laboratory experiments. |
|
|
|
|
| Course Content and Homework/Schedule/Tests Schedule |
| Week |
Course Content |
| Week 1 |
What is chemical biology?
Nucleic acid structure and synthesis
No class (Mid-Autumn Festival)
DNA sequencing and DNA mimetics
RNA: RNA interference
Ribozymes and aptamers
Carbohydrates: structure
Carbohydrates: biosynthesis and function
Carbohydrates: applications
Carbohydrates: chemical synthesis
Introduction to lipids and membranes
Carbohydrates: chemical synthesis
Lipid structure
Protein synthesis and folding
Protein degradation and quality control
Protein misfolding and neurodegeneration
Producing proteins and peptides
Chromatography and electrophoresis
Protein extraction, subcellular fractionation, centrifugation
Antibody technologies
Humanized antibody
Structural Biology
Labeling with fluorophores and biotin
Fluorescent proteins and FRET
Basics of Fluorescence Microscopy
Super-resolution Optical Microscopy
Bioorthogonal chemistry; Active site probe
Mass spec: instrumentation
Mass spec of proteins
Mass spec and protein quantification
Post-translational modifications
Biotech job market and industry outlook
|
| Week 2 |
|
| Week 3 |
|
| Week 4 |
|
| Week 5 |
|
| Week 6 |
|
| Week 7 |
|
| Week 8 |
|
| Week 9 |
|
| Week 10 |
|
| Week 11 |
|
| Week 12 |
|
| Week 13 |
|
| Week 14 |
|
| Week 15 |
|
| Week 16 |
|
| Week 17 |
|
| Week 18 |
|
|
| Evaluation |
| 期中、期末測驗以及課堂報告 |
| Textbook & other References |
"Essentials of Glycobiology" 2nd Edition, by Varki A., Cummings R.D., Esko
J.D., et al., editors.Cold Spring Harbor (NY): Cold Spring Harbor Laboratory
Press; 2009.
"Biochemistry" 7yh ed., by J. M. Berg, J. L. Tymocko and L. Stryer. Freeman, New York, 2012.
|
| Teaching Aids & Teacher's Website |
| 教師自製講義 |
| Office Hours |
| 未限定時間 |
| Sustainable Development Goals, SDGs |
| | include experience courses：N |
|