| Relevance of Course Objectives and Core Learning Outcomes(%) |
Teaching and Assessment Methods for Course Objectives |
| Course Objectives |
Competency Indicators |
Ratio(%) |
Teaching Methods |
Assessment Methods |
| This class taught students to learn how to find the literatures of animal virology, understand the research method of virology, and learn the progress and development of this field. |
| 1.Professional knowledge in microbiology and public health. |
| 2.Ability to conduct experiments in microbiology, public health, biochemistry and molecular biology. |
| 3.Ability to read research articles in English or Chinese. |
| 4.Ability of logical thinking and lifelong learning. |
|
|
| Discussion |
| topic Discussion/Production |
|
| Oral Presentation |
| Attendance |
| Written Presentation |
|
| Course Content and Homework/Schedule/Tests Schedule |
| Week |
Course Content |
| Week 1 |
1.The genetic stability, replication kinetics and cytopathogenicity of recombinant avian coronaviruses with a T16A or an A26F mutation within the E protein is cell-type dependent. Viruses 14:1784 |
| Week 2 |
2.Interaction between lactobacilli and chicken macrophages induce antiviral responses against avian influenza virus. Research in Veterinary Science 125:441-450 |
| Week 3 |
3.Spontaneous and targeted mutations in the decapping enzyme enhance replication of modified vaccinia virus Ankara (MVA) in monkey cells. Journal of Virology 95:e01104-21 |
| Week 4 |
4.Enhanced neutralization potency of an identical HIV neutralizing antibody expressed as different isotypes is achieved through genetically distinct mechanisms. Scientific Reports 12:16473 |
| Week 5 |
5.SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules Signal Transduction and Targeted Therapy 7:22 |
| Week 6 |
6.A poxvirus decapping enzyme colocalizes with mitochondria to regulate RNA metabolism and translation and promote viral replication. mBio 13(3):e0030022 |
| Week 7 |
7.Evasion of a human cytomegalovirus entry inhibitor with potent cysteine reactivity is concomitant with the utilization of a heparan sulfate proteoglycan-independent route of entry. Journal of Virology 94:e02012-19 |
| Week 8 |
8.Virulence differences of mpox (monkeypox) virus clades I, IIa, and IIb.1 in a small animal model. PNAS 120:e2220415120 |
| Week 9 |
9.Gut microbiota is associated with protection against Marek’s disease virus infection in chickens. Virology 553:122-130 |
| Week 10 |
10.Vaccinia virus D10 has broad decapping activity that is regulated by mRNA splicing. PLOS Pathogens 18(2):e1010099 |
| Week 11 |
11.Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication. iScience 25:104136 |
| Week 12 |
12.Xenogenic rolling-circle replication of a synthetic beak and feather disease virus genomic clone in 293TT mammalian cells and Nicotiana benthamiana. Journal of General Virology 98:2329-2338 |
| Week 13 |
13.Role of stress granules in suppresing viral replication by the infectious bronchitis virus endonuclease. Journal of Virology 96:e0068622 |
| Week 14 |
14.The molecular basis for SARS-CoV-2 binding to dog ACE2. Nature Communications 12:4195 |
| Week 15 |
Student presentation (I) |
| Week 16 |
Student presentation (II) |
| Week 17 |
Student presentation (III) |
| Week 18 |
Final discussion |
|
| Evaluation |
| Presentation performance (100%) |
| Textbook & other References |
| mBio, Scientific Report, Signal Transduction and Targeted Therapy, Research in Veterinary Science, PNAS, PLOS Pathogens, Journal of General Virology, Journal of Virology, Nature Communications |
| Teaching Aids & Teacher's Website |
|
| Office Hours |
| Friday 16:00-17:00 |
| Sustainable Development Goals, SDGs |
| include experience courses：N |
|