NCHU Course Outline
Course Name (中) 高等醫藥化學(一)(6533)
(Eng.) Advanced Medicine-Drug Chemistry (I)
Offering Dept Department of Chemistry
Course Type Elective Credits 3 Teacher 鍾靈
Department Department of Chemistry/Graduate Language 中/英文 Semester 2025-FALL
Course Description Drug design and development from lab to clinic
Prerequisites
self-directed learning in the course Y
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
Understand the process of drug discovery and de-velopment (from lab to clinic)
1.Capability of professional knowledge in chemistry
3.Capability of comprehension and analysis of science mathematics
60
40
topic Discussion/Production
Exercises
Discussion
Lecturing
Written Presentation
Oral Presentation
Assignment
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 Introduction of drug discovery and development process from Bench to Bedside
Week 2 Computer-Aided Rational Drug Design
Week 3 Cause of disease and Therapeutic Drug Targets
Week 4 Animal studies to bridge translational gap between basic scientific discoveries and human medicine
Week 5 Lead Discovery: High-Throughput Screening (HTS)
Week 6 Drug Physiological/Physicochemical Properties: The physical and chemical characteristics of a drug that influence its interaction with the body
Week 7 Hit-to-Lead (H2L) Selection and Lead Optimization
Week 8 Oral Presentation and Mid-Term Evaluation
Week 9 Pharmacology: How Drugs Affect Living Organisms
Pharmacokinetics (PK) & Pharmacodynamics (PD)
Week 10 IND-Enabling Toxicology Studies Essential For Safeguarding Patient Health
Week 11 Drug Formulation: Turning API (Active Pharmaceutical Ingredient) into Effective Medi-cines
Week 12 Introduction of Human Clinical Trial (Phase I-III)
Week 13 Intellectual Property (IP) Rights and Patent Application
Week 14 Leadership, Project Development and Team Collaboration
Week 15 Oral Presentation: Making Improvement
Week 16 Final Evaluation and Constructive Feedback
self-directed
learning
   03.Preparing presentations or reports related to industry and academia.

Evaluation

Textbook & other References

Teaching Aids & Teacher's Website

Office Hours

Sustainable Development Goals, SDGs(Link URL)
03.Good Health and Well-Beinginclude experience courses:N
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Update Date, year/month/day:2025/09/02 10:17:35 Printed Date, year/month/day:2025 / 9 / 09
The second-hand book website:http://www.myub.com.tw/