| Relevance of Course Objectives and Core Learning Outcomes(%) |
Teaching and Assessment Methods for Course Objectives |
| Course Objectives |
Competency Indicators |
Ratio(%) |
Teaching Methods |
Assessment Methods |
| Study the basic principles of toxicology and focus on the characteristics of environmental pollutants in relation to the underlying mechanisms by which harmful toxic substances exert their toxic action on living organisms .研習毒理學之基本原理，並針對環境污染物之特性，個別深入探討環境中有害毒性物質其致毒機轉。 |
| 1.Expertise in environmental engineering. |
| 2.Ability to plan and execute research on environmental engineering topics. |
| 3.Ability to write professional papers in environmental engineering. |
| 4.Innovative thinking and independent problem-solving skills. |
| 5.Ability to coordinate and integrate with people from different fields |
| 6.Good international outlook. |
| 7.Ability to lead, manage and plan. |
| 8.Ability to grow through lifelong self-learning. |
|
|
| Discussion |
| Networking/Distance Education |
| Lecturing |
|
| Assignment |
| Attendance |
| Written Presentation |
| Quiz |
|
| Course Content and Homework/Schedule/Tests Schedule |
| Week |
Course Content |
| Week 1 |
週次(week) 單元名稱與內容(subject and content)
01 毒理學簡介流行病學及毒理學測試研究 Lecture 1-Introduction to Toxicology, Epidemiological Studies, Toxicological Studies |
| Week 2 |
02 曝露路徑及劑量效應研究 Lecture 2-Introduction to Routes of Exposure; The Dose-Response Relationship |
| Week 3 |
03 分子生物學簡介 Lecture 3- Introduction to Molecular and Cell Biology |
| Week 4 |
04 人體生理學簡介 Lecture 4- Introduction to Human Physiology |
| Week 5 |
05 毒理動力學Lecture 5 –Toxicokinetics (I): Absorption, Distribution, Metabolism, and Elimination of Toxics |
| Week 6 |
06 毒理動力學 Lecture 6 - Toxicokinetics (II): Metabolic Bioactivation: Microsomal Cytochrome P450s and Phase II Enzymes |
| Week 7 |
07 曝露路徑及劑量與效應相關性特論 Lecture 7- Special topics in Routes of Exposure and The Dose-Response Relationship |
| Week 8 |
08 毒理效應學-標的器官效應 Lectrue 8-Toxicodynamics-Target Organ Effects |
| Week 9 |
09 期中考 Midterm Exam |
| Week 10 |
10 (I)毒性效應學-基因突變 Lecture 9- Toxicodynamics-Mutagenesis |
| Week 11 |
(II)毒性效應學-致畸作用Lecture 9- Toxicodynamics-Teratogenesis |
| Week 12 |
(III)毒性效應學-致癌作用Lecture 9- Toxicodynamics- Carcinogenesis |
| Week 13 |
11 毒性物質之簡介 (I) 室內與室外空氣污染物石油蒸餾物金屬及農藥 Lecture 10-Survey of Toxic Substances (I): Outdoor air pollutants; Indoor air pollutants; Petroleum distillates; Metals ; Pesticides. |
| Week 14 |
12 毒性物質之簡介(II)多環芳香族碳氫化物及鹵族芳香族化物Lecture 11-Survey of Toxic Substances (II): polycyclic aromatic hydrocarbons (PAHs) and halogenated aromatic hydrocarbons (including dioxins PCBs and pentachlorophenol) |
| Week 15 |
13 毒性物質之簡介 (III) 鄰苯二甲酸酯以及藥物及個人衛生保健品Lecture 12-Survey of Toxic Substances (III): Phthalates and other pharmaceutical personal care products (PPCPs) or emergent contaminants |
| Week 16 |
14 (I)基因多型性及 Lecture 13-Genetic polymorphisms |
| Week 17 |
(II)健康風險評估 Lecture 13-Health Risk Assessment |
| Week 18 |
15 期末考 Final Exam |
|
| Evaluation |
| mid-term and final examination plus term papers (作業) |
| Textbook & other References |
1. Basic Toxicology, Frank C. Lu. Four edition, 2002.
2. Casarett and Doull's Toxicology, Amdur et al. 2018.
|
| Teaching Aids & Teacher's Website |
| Journal articles |
| Office Hours |
| To be arranged 依本系所規定的輔導時間 |
| Sustainable Development Goals, SDGs |
| | include experience courses：N |
|