NCHU Course Outline
Course Name (中) 基因轉錄機制(6668)
(Eng.) Mechanism of Transcription
Offering Dept Graduate Institute of Biochemistry
Course Type Elective Credits 3 Teacher YI-YING CHIOU
Department Graduate Institute of Biochemistry/Graduate Language English Semester 2026-SPRING
Course Description Gene expression affects all biological processes in the cells. Understanding how the mechanisms of transcription help understand the regulation of biological functions through transcriptional regulation.
Prerequisites
self-directed learning in the course Y
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
This course aims to understand the mechanism of how cells regulate the expression of genes in the cells. Through lectures, discussion and presentation, students would understand the mechanisms and the research approaches about transcriptional regulation.
Lecturing
Discussion
Attendance
Oral Presentation
Assignment
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 Course Introduction
Week 2 Overview: What is gene expression
Week 3 The impact of chromatin
Week 4 The basal transcriptional machinery
Week 5 Transcription factors
Week 6 Linking signal transduction and gene regulation
Week 7 Switching genes on and off: The example of nuclear receptor
Week 8 Mapping to the genome
Week 9 self-direct learning
Week 10 Chromatin modifier
Week 11 Genomic imprinting
Week 12 The epigenome
Week 13 Chromatin remodeling architecture
Week 14 Chromatin architecture
Week 15 Non-coding RNA
Week 16 Final presentation
self-directed
learning
   03.Preparing presentations or reports related to industry and academia.

Evaluation
Attendance & Engagement 35%
Final presentation 30%
In/Off-class tasks 35%
Textbook & other References
Mechanisms of Gene Regulation, 2nd Edition, Springer
Teaching Aids & Teacher's Website
Mechanisms of Gene Regulation, 2nd Edition, Springer
Office Hours
Thursday 12:00-13:00
Sustainable Development Goals, SDGs(Link URL)
03.Good Health and Well-Beinginclude experience courses:N
Please respect the intellectual property rights and use the materials legally.Please respect gender equality.
Update Date, year/month/day:2026/02/23 10:20:12 Printed Date, year/month/day:2026 / 3 / 10
The second-hand book website:http://www.myub.com.tw/