NCHU Course Outline
Course Name (中) 表顯遺傳學(6627)
(Eng.) Epigenetics
Offering Dept Graduate Institute of Molecular Biology
Course Type Elective Credits 2 Teacher YANG,WEN-MING
Department Graduate Institute of Molecular Biology/Graduate Language English Semester 2025-SPRING
Course Description To learn all the updating concepts about epigenetics from molecular level. (http://web.nchu.edu.tw/~yangwm/2361/)

Prerequisites
self-directed learning in the course Y
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
To learn current knowledge about Epigenetics.

1.Competence in Molecular Biology
2.Competence in Biotechnology
3.Abilities in scientific argumentation and problem identification
4.Skills in organization, presentation and communication
30
20
30
20
Lecturing
Discussion
Written Presentation
Oral Presentation
Attendance
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 Part I: The Notion of Epigenetics
1. A Historical Overview
Week 2 2. Cytoplasmic Epigenetics (I): Proteins Acting as Genes
Week 3 3. Cytoplasmic Epigenetics (II): Inheritance by Cytoplasmic Continuity
Week 4 Part II: Epigenetics Paradigms
4. A Perspective on ideas on X-Chromosome
Week 5 5. Genomic Imprinting: History and Embryology
Week 6 6. Genomic Imprinting and its Regulation
Week 7 7. Epigenetic Regulation of Phenotype
Week 8 8. RNAi and Heterochromatin
Week 9 Part III: Epigenetics Mechanisms
9. DNA Methylation
Week 10 10. Polycomb Epigenetic Mechanisms
Week 11 11. Histone Modifications and Prospects for an Epigenetic Code
Week 12 12. Epigenetic Control by Histone Methylation
Week 13 13. Histone Dynamics, Heritability and Variants
Week 14 14. Nuclear Organization and Gene Expression
Week 15 Part IV: Epigenetics: Heritability and Reversibility
15. Nuclear Cloning, Stem Cells and Epigenetic Reprogramming
Week 16 16. Stem Cell Memory
Week 17 17. Review and writing help
Week 18 18. Review and writing
Evaluation
Attention and Final Review Paper

Textbook & other References
Handout editing from Wen-Ming Yang. Whether this class is open or not will dependent on how many students take in. It will be determined later when the class-taken is finished.

Teaching Aids & Teacher's Website
https://web2.nchu.edu.tw/~yangwm/6619/

Office Hours
星期二中午12點30分-下午1點。
Sustainable Development Goals, SDGs
include experience courses:N
Please respect the intellectual property rights and use the materials legally.Please repsect gender equality.
Update Date, year/month/day:None Printed Date, year/month/day:2025 / 1 / 22
The second-hand book website:http://www.myub.com.tw/