| Relevance of Course Objectives and Core Learning Outcomes(%) |
Teaching and Assessment Methods for Course Objectives |
| Course Objectives |
Competency Indicators |
Ratio(%) |
Teaching Methods |
Assessment Methods |
| Special Topics in One Carbon Metabolism |
|
|
| Discussion |
| Lecturing |
| topic Discussion/Production |
|
| Study Outcome |
| Written Presentation |
| Attendance |
| Oral Presentation |
|
| Course Content and Homework/Schedule/Tests Schedule |
| Week |
Course Content |
| Week 1 |
Introduction |
| Week 2 |
Overview |
| Week 3 |
Nutrient-Genome Interactions in 1C metabolism in Human Health. Lecture |
| Week 4 |
Nutrient-Genome Interactions in 1C metabolism in Human Health. Case Study |
| Week 5 |
Drug-Genome Interactions in 1C metabolism. Case Study: Drug and gene interactions (DMARDs) |
| Week 6 |
Drug impacts on 1C metabolism. Case Study: Biologics (Jaki, anti-TNF, anti-IL6)
Enzymes in 1C Metabolism & Their Interactions with Cofactors. Lecture |
| Week 7 |
Partitioning in 1C Metabolism and Their Interactions with Cofactors. Lecture
|
| Week 8 |
Partitioning in 1C Metabolism and Their Interactions with Cofactors. Case: Study: Exercise |
| Week 9 |
Metabolites in 1C metabolism Lecture:
Metabolites in 1C Metabolism. Case Study
|
| Week 10 |
Folate and Folic Acid in Cancer. Lecture
Folate and Folic Acid in Cancer. Case Study: GNMT I, II, III, and what’s next?
|
| Week 11 |
Dietary factors that affect 1C Metabolism, and the gene-nutrient interactions
Factors affect 1C Metabolism-Energy Expenditure (KDIFCR) |
| Week 12 |
1C Metabolism in Human Diseases. Lecture: Statistical Analyses for case control, RCT. Case Study: AJM, JN, Gut, CCR, WJG |
| Week 13 |
1C Metabolism in Human Diseases. Lecture: B6 vitamers, Human Study Design |
| Week 14 |
1C Metabolism in Human Diseases. Case Study: B6 in inflammation |
| Week 15 |
1C Metabolism in Human Diseases. Lecture and case Study:1C in inflammation
Term paper and homework discussions (I) |
| Week 16 |
C Metabolism in Human Diseases. Lecture and case Study: OCM during aging
Term paper and homework discussions (II)
Term paper and homework discussions (III)
Term paper and homework discussions (IV) |
self-directed
learning |
|
|
| Evaluation |
| In-class presentation (50%); class participation and discussions (25%); Term paper (25%) |
| Textbook & other References |
1. Lecture printouts.
2. Handbook of Vitamins ISBN: 0-8247-0428-2, Third Edition (Clinical Nutrition in Health and Disease) by Robert B. Rucker (Author), John W. Suttie (Author), Donald B. McCormick (Author)
3. Advanced Nutrition and Human Metabolism. 5th ed. Seattle, WA. Nutritional biochemistry by Tom Brody. 2nd. Ed
4. Food and Nutrition in Translational Medicine Workshop from Stover PJ
5. Selected recent papers in the field. |
| Teaching Aids & Teacher's Website |
Lecture printouts
https://sites.google.com/email.nchu.edu.tw/chiang-lab-2021/publish?authuser=0 |
| Office Hours |
| Monday Noon-1 pm |
| Sustainable Development Goals, SDGs(Link URL) |
| include experience courses：N |
|