NCHU Course Outline
Course Name (中) 天然物生物活性研究(6945)
(Eng.) Bioactivity Research of Natural Products
Offering Dept Master Program in Specialty Crops and Metabolomics
Course Type Elective Credits 3 Teacher YEN, PEI-LING
Department Master Program in Specialty Crops and Metabolomics/Graduate Language 中/英文 Semester 2026-SPRING
Course Description This course introduces the use of model organisms in the evaluation of biological activity of natural products. The course emphasizes experimental design, phenotypic assays, and molecular endpoints relevant to oxidative stress, aging, neurodegeneration, and metabolism. Students will learn how to utilize model organisms for in vivo screening, pathway analysis, and translational research through hands-on case studies, literature discussion, and project presentations.
Prerequisites
self-directed learning in the course Y
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
Students will be able to:
1. Describe the characteristics and advantages of model organisms.
2. Interpret biological effects and molecular mechanisms of natural compounds.
Discussion
Lecturing
Written Presentation
Oral Presentation
Assignment
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 Introduction to Natural Product Bioactivity and Model Systems
Week 2 Life Cycle, Handling, and Maintenance of Model Organisms
Week 3 Aging and Longevity Assays in Bioactivity Evaluation
Week 4 Stress Response Pathways: Oxidative, Heat, ER Stress
Week 5 Assessing Metabolic Health
Week 6 Neurobehavioral Assays and Neurotoxicity Screening
Week 7 Natural Products and Immune Modulation
Week 8 Mid-term: Experimental Design Proposal
Week 9 Genetic and Molecular Tools for Functional Analysis
Week 10 Molecular Pathways Targeted by Natural Compounds I
Week 11 Molecular Pathways Targeted by Natural Compounds II
Week 12 Omics Platforms for Natural Product Research I
Week 13 Omics Platforms for Natural Product Research II
Week 14 Experimental Design, Reproducibility, and Data Interpretation
Week 15 Applications for Functional Food and Preventive Health
Week 16 Student Presentations
self-directed
learning
   03.Preparing presentations or reports related to industry and academia.
The final project of this course promotes student learning through self-directed research proposal development, requiring students to independently select a natural product or extract, conduct literature analysis, and integrate bioactivity evaluation with experimental design.
Evaluation
Midterm assessment (exam or written assignments): 30%
Case study presentation: 40%
Final written report: 30%.
Textbook & other References
Atta-ur-Rahman (Ed.). Studies in Natural Products Chemistry (Book series). Elsevier.
WormBook: The Online Review of C. elegans Biology. http://www.wormbook.org
Teaching Aids & Teacher's Website
Lecture slides and selected research articles.
Office Hours
After class
Sustainable Development Goals, SDGs(Link URL)
03.Good Health and Well-Beinginclude experience courses:N
Please respect the intellectual property rights and use the materials legally.Please respect gender equality.
Update Date, year/month/day:2026/02/06 12:44:02 Printed Date, year/month/day:2026 / 3 / 10
The second-hand book website:http://www.myub.com.tw/