NCHU Course Outline
Course Name (中) 細胞訊息傳導與調控(6498)
(Eng.) Cellular Signal Transduction and Regulation
Offering Dept Graduate Institute of Veterinary Pathobiology
Course Type Elective Credits 2 Teacher HSUAN,SHIH-LING
Department Graduate Institute of Veterinary Pathobiology/Graduate Language 中/英文 Semester 2025-SPRING
Course Description 介紹細胞訊息傳導路徑及相關調控機制,並藉由文獻的研讀與討論,瞭解訊息傳導研究之相關實驗設計與方法。
This course will introduce the knowledge of cellular signal transduction pathways and their regulation mechanisms. Through reading and discussion of research articles, students will further understand the experimental design and methods for study of signal transduction.
Prerequisites
self-directed learning in the course N
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
讓學生瞭解重要訊息傳導路徑及其調控機制
This course will provide students the basic knowledge of cellular signal transduction pathways and their regulation mechanisms.
2.Experimental technique for veterinary pathology, microbiology and bio-medicine
3.Training of biomedical pathology, pathogenesis research and biotechnology research and development of technology and other key capabilities
40
60
Lecturing
Discussion
Quiz
Oral Presentation
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 1. Function and Structure of Signaling Pathways
Week 2 2. G-Protein Coupled Signal Transduction Pathways
Week 3 3. Intracellular Messenger Substances: Second Messengers (I)
Week 4 4. Intracellular Messenger Substances: Second Messengers (II)
Week 5 5. Signal Transmission via Receptor Tyrosine Kinases
Week 6 6. Membrane Receptors with Associated Tyrosine Kinase Activity
Week 7 7. Ser/Thr-Specific Protein Kinases and Protein Phosphatases (I)
Week 8 8. Ser/Thr-Specific Protein Kinases and Protein Phosphatases (II)
Week 9 9. Midterm Examination
Week 10 10.Signaling by Nuclear Receptors and Other Receptor Classes
Week 11 11. Extrinsic Apoptotic Pathway
Week 12 12. Intrinsic Apoptotic Pathway
Week 13 13. Jak-Stat Signaling Pathway
Week 14 14. Proteasome/NF-κB Signaling Pathway
Week 15 15. Research Article Discussion (I)
Week 16 16. Research Article Discussion (II)
Week 17 17. Research Article Discussion (III)
Week 18 18. Final Examination
Evaluation
測驗、口頭報告
Examination and oral presentation
Textbook & other References
1. Biochemistry of Signal Transduction and Regulation, Third Edition (Archive Edition), 2003, Gerhard Krauss, Wiley-VCH Verlag GmbH.
2. Structure and Function in Cell Signaling, 2008, J. Nelson, John Wiley & Sons.
3. Guide to Signal Pathways in Immune Cells, 2009, E. N. Wardle, Human Press.
4. Apoptosis, Cell Engineering, V. 4, 2004, M. Al-Rubeai & M. Fussenegger, Kluwer Academic Publishers.
5. Journal Articles.
Teaching Aids & Teacher's Website
iLearning
Office Hours
By appointment
Sustainable Development Goals, SDGs
 include experience courses:N
Please respect the intellectual property rights and use the materials legally.Please repsect gender equality.
Update Date, year/month/day:None Printed Date, year/month/day:2025 / 1 / 22
The second-hand book website:http://www.myub.com.tw/