NCHU Course Outline
Course Name (中) 動物病毒學文獻探討(一)(6279)
(Eng.) Seminar on Animal Virology (I)
Offering Dept Department of Veterinary Medicine
Course Type Elective Credits 1 Teacher CHI-YOUNG WANG ect.
Department Graduate Institute of Veterinary Pathobiology/Graduate Language English Semester 2025-SPRING
Course Description This class was offered to the undergraduate students to equip them with basic knowledge about the animal virology.
Prerequisites
self-directed learning in the course N
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
To teach students how to read, analyze, and write the scientific papers about the animal virology.
2.Experimental technique for veterinary pathology, microbiology and bio-medicine
3.Training of biomedical pathology, pathogenesis research and biotechnology research and development of technology and other key capabilities
50
50
Discussion
Lecturing
Oral Presentation
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 1.Canarypox and fowlpox viruses as recombinant vaccine vectors: a biological and immunological comparison. Antiviral Res. 88:53-63.
Week 2 2.New insight into avian papillomavirus ecology and evolution from characterization of novel wild bird papillomaviruses. Front. Microbiol. 10:701
Week 3 3.Apoptosis triggered by ORF3 proteins of the circoviridae family. Frontiers in cellular and infection microbiology 10:609071
Week 4 4.Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek’s disease virus. J. Virol. 74:3605-3612
Week 5 5.Cell permeabilization by poliovirus 2B viroporin triggers bystander permeabilization in neighbouring cells through a mechanism involving gap junctions. Cell. Microbiol. 12:1144-1157.
Week 6 6.Inhibition of anti-viral stress granule formation by coronavirus endoribonuclease nsp15 ensures efficient replication. PLoS Pathog. 17(2):e1008690
Week 7 7.The herpes simplex virus host shutoff (vhs) RNase limits accumulation of double stranded RNA in infected cells: evidence for accelerated decay of duplex RNA. PLoS Pathog. 15(10):e1008111
Week 8 8.Recombinant infectious bronchitis coronavirus Beaudette with the spike protein gene of the pathogenic M41 strain remains attenuated but induces protective immunity. Journal of Virology 78:13804-13811
Week 9 9.Characterization, functional and signaling elucidation of pigeon (Columba livia) interferon-alpha: knockdown p53 negatively modulates antiviral response. Dev. Comp. Immunol. 90:29-40
Week 10 10.Recovirus NS1-2 has viroporin activity that induces aberrant cellular calcium signaling to facilitate virus replication. mSphere 4:e00506-19
Week 11 11.Genome-wide classification of type I, type II, and type III interferon-stimulated genes in chicken fibroblasts. Vaccines 7:160
Week 12 12.Interferon gamma prevents infectious entry of human papillomavirus 16 via an L2-dependent mechanism. J. Virol. 91:e00168-17
Week 13 13.Encephalomyocarditis virus viroporin 2B activates NLRP3 inflammasome. PLoS Pathog. 8:e1002857
Week 14 14.A reporter system for assaying influenza virus RNP functionality based on secreted Gaussia luciferase activity. Virol. J. 8:29
Week 15 Student presentation (I)
Week 16 Student presentation (II)
Week 17 Student presentation (III)
Week 18 Final discussion
Evaluation
Presentation performance (100%)
Textbook & other References
Antiviral Res
Front. Microbiol.
J. Virol.
Cell. Microbiol.
Plos Pathog.
Dev. Comp. Immunol.
Vaccines
Virol.
Teaching Aids & Teacher's Website

Office Hours
Friday 16:00-17:00
Sustainable Development Goals, SDGs
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