NCHU Course Outline
Course Name (中) 奈米藥物輸送概論(3330)
(Eng.) Introduction of Nanotechnology in Drug Delivery
Offering Dept Department of Chemical Engineering
Course Type Elective Credits 3 Teacher Chian-Hui Lai
Department Department of Chemical Engineering/Undergraduate Language 中/英文 Semester 2025-SPRING
Course Description (中)本課程目標將由科學和技術上討論奈米科技及其在生醫上的應用,使奈米生醫科技不甚熟悉的學生能深入了解奈米生醫科技。課程會介紹四主題包含:
(1) 細胞與生物體。
(2) 奈米科技於藥物輸送基礎的概念。
(3) 奈米科技應用於藥物輸送,包含小分子、短鏈胜肽、蛋白質與核酸。
(4) 介紹目前最新奈米藥物發展現狀與未來展望。

(Eng.) This course aim to provide students with a basic understanding of the nanoparticle or nano-scale carrier as a drug delivery system. As part of this course, students will be introduced to four parts:
(1) Cell and its biology
(2) Fundamentals of Nanotechnology in Drug Delivery.
(3) Nanotechnology for the Delivery of Small Molecules, Peptide, Protein and Nucleic Acids.
(4) A Look to the Future of Nanotechnology in Drug Delivery.
Prerequisites
self-directed learning in the course Y
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
(中) 介紹奈米粒子當作藥物載體的優勢與其製備方式與應用。

(Eng.) Introduction the advantage of nanoparticles as drug delivery system and their preparations and applications.
1.Solid foundations on fundamental scientific and professional chemical engineering knowledge.
2.Substantiated expertise on distinct areas including biotechnology, polymer science, and precision chemical processing.
3.Proficiency of analyzing problems and identifying key points with rigorous logic.
4.Courage to confront challenges and initiate discoveries.
5.Philosophy of interdisciplinary study and proactive learning.
6.Attitude of active participation and efficient communication.
8.Awareness of environmental responsibilities and globalization trend.
15
20
10
15
30
5
5
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 課程介紹Introduction of Nanotechnology in Drug Delivery
Week 2 Cell Biology
Week 3 Drug Delivery Systems: Possibilities and Challenges
Week 4 Drug Delivery Systems: Possibilities and Challenges
Week 5 Nanoparticles in Circulation: Blood Stability
Week 6 How do Nanoparticles (NPs) Pass Barriers?
Week 7 Nano Delivery Systems
Week 8 midterm exam
Week 9 Controlled Released from Hydrogel
Week 10 Fundamentals of Stimuli-responsive Drug and Gene Delivery Systems
Week 11 Enzyme-responsive Drug Delivery Systems
Week 12 Stimuli-responsive Material Inspired Drug Delivery Systems and Devices
Week 13 Stimuli-responsive Materials in Theranostics
Week 14 Stimuli-responsive Materials in Theranostics
Week 15 Future Perspective on the Smart Delivery of Biomolecules / Regulatory and Commercialization Challenges
with Stimuli-responsive Nanomedicines
Week 16 期末考
Week 17 Discussion and student report (I)
Week 18 Discussion and student report (II)
Evaluation
期中考 30%
期末考 30%
報告 20%
課堂表現 20%
Textbook & other References
1. 書名:Drug Delivery Systems 作者: Pieter Stroeve (UC Davis) and Morteza Mahmoudi (Tehran University of Medical Sciences, Iran & Harvard Medical School, USA) 書局: World Scientfic 出版年: 2018 ISBN: 978-981-3201-06-4
2. 書名: Stimuli-responsive drug delivery systems作者: Singh, Amit; Amiji, Mansoor M. 書局: Royal Society of Chemistry 出版年 2018
3.書名:Bioorganic chemistry : highlights and new aspects. 作者Diederichsen, Ulf (EDT)/ Lindh書局Wiley-VCH, 出版年:1999
Teaching Aids & Teacher's Website
https://chianhuilai.wixsite.com/my-site
Office Hours
周三上午9:00
Sustainable Development Goals, SDGs(Link URL)
02.Zero Hunger   03.Good Health and Well-Being   04.Quality Education   09.Industry, Innovation and Infrastructureinclude experience courses:N
Please respect the intellectual property rights and use the materials legally.Please respect gender equality.
Update Date, year/month/day:2025/02/17 12:16:15 Printed Date, year/month/day:2025 / 4 / 19
The second-hand book website:http://www.myub.com.tw/