| Relevance of Course Objectives and Core Learning Outcomes(%) |
Teaching and Assessment Methods for Course Objectives |
| Course Objectives |
Competency Indicators |
Ratio(%) |
Teaching Methods |
Assessment Methods |
| The goal of this course will guide the students with comprehensive knowledge to perform data exploration |
| 1.Professional knowledge in microbiology and public health. |
| 2.Ability to conduct experiments in microbiology, public health, biochemistry and molecular biology. |
| 3.Ability to read research articles in English or Chinese. |
| 4.Ability of logical thinking and critical thinking on experimental results. |
| 5.Ability of independent thinking, innovational R&D and lifelong learning. |
|
|
| topic Discussion/Production |
| Lecturing |
| Other |
| Practicum |
| Discussion |
| Exercises |
|
| Assignment |
| Oral Presentation |
| Attendance |
| Written Presentation |
|
| Course Content and Homework/Schedule/Tests Schedule |
| Week |
Course Content |
| Week 1 |
Introduction
|
| Week 2 |
Molecular typing techniques for epidemiological investigation and surveillance |
| Week 3 |
Basic concepts of molecular evolution |
| Week 4 |
Sequence alignment and comparison |
| Week 5 |
Nucleotide substitution model |
| Week 6 |
tree inferring method: UPGMA and neighbor joining |
| Week 7 |
tree inferring method: parsimony |
| Week 8 |
tree inferring method: maximum likelihood and Bayeisan method |
| Week 9 |
Basic concepts in viral evolution |
| Week 10 |
Midterm exam |
| Week 11 |
Viral quasispecies and fitness |
| Week 12 |
Phylodynamics and coalescent theory |
| Week 13 |
Phylogeography |
| Week 14 |
Metagenomic sequence analysis |
| Week 15 |
Software demo and practice |
| Week 16 |
Final exam |
| Week 17 |
autonomous learning (I) |
| Week 18 |
autonomous learning (II) |
|
| Evaluation |
on-site participation(50%) Class attendance (50%)
oral presentation(50%)
|
| Textbook & other References |
1. Esteban Domingo, Robert Webster and John Holland. Origin and evolution of viruses. Academic Press, London, UK, 1999)
2. Marco Salemi and Anne-Mieke Vandamme. The Phylogenetic Handbook. A practical approach to DNA and protein phylogeny. Cambridge University Press, New York, USA, 2003.
|
| Teaching Aids & Teacher's Website |
|
| Office Hours |
| Monday-Friday 12-1pm |
| Sustainable Development Goals, SDGs |
| include experience courses：N |
|