NCHU Course Outline

Course Name	(中) 高等病理生物學(6506)
Course Name	(Eng.) Advanced Pathobiology
Offering Dept	Graduate Institute of Veterinary Pathobiology
Course Type	Required	Credits	2	Teacher	WU,HUNG-YI ect.
Department	Graduate Institute of Veterinary Pathobiology/Graduate	Language	English	Semester	2026-FALL
Course Description	The course covers two parts: cell biology and pathogenesis of diseases. The first part lets students understand basic cell biology with the emphasis on cellular posttranscriptional regulators. The topics of second part focus on its relationship with pathogenesis of diseases. Topics of current interest in the field are selected and reviewed by the student. Presentations are followed by a general informal discussion. Under certain circumstances, reports of presentation may be made by students.
Prerequisites				self-directed learning in the course	Y

Relevance of Course Objectives and Core Learning Outcomes(%)

Teaching and Assessment Methods for Course Objectives

Course Objectives

Competency Indicators

Ratio(%)

Teaching Methods

Assessment Methods

1. To enable the students to understand basic cell biology with the emphasis on cellular pathogenesis of diseases.

1.Applied professional knowledge in animal medicine, veterinary pathology and biological medicine

3.Training of biomedical pathology, pathogenesis research and biotechnology research and development of technology and other key capabilities

Lecturing

Quiz

Written Presentation

Course Content and Homework/Schedule/Tests Schedule

Week	Course Content
Week 1	Introduction to the cell I
Week 2	Introduction to the cell II
Week 3	DNA Structure and Function I
Week 4	DNA Structure and Function II
Week 5	DNA Structure and Function III
Week 6	Transcription and organization of eukaryotic gene sequences I
Week 7	Transcription and organization of eukaryotic gene sequences II
Week 8	Transcription and organization of eukaryotic gene sequences III
Week 9	Molecular biology of messenger RNA and non-coding RNAs I
Week 10	Molecular biology of messenger RNA and non-coding RNAs II
Week 11	Midterm examination
Week 12	MicroRNA and apoptosis
Week 13	MicroRNA and cancer I
Week 14	MicroRNA and cancer II
Week 15	MicroRNA and cancer III
Week 16	MicroRNAs and vascular diseases, inflammation, angiogenesis, heart disease MicroRNA and CNS normal development and diseases Oral presentation
self-directed learning

Evaluation

Examination, power point presentation, writing assignment

Textbook & other References

1. Garzon R, Fabbri M, Cimmino A, Calin G. A., and Croce C. M. 2006.
MicroRNA expression and function in cancer. Trends Mol Med.12(12);580-7
2. Lvnam-Lennon N, Maher S. G., and Revnolds J. V. 2009. The roles of
microRNA in cancer and apoptosis. 84(1):55-71
3. Jan Barciszewski and Volker A. Erdmann. 2003. Non-Coding RNAs:
Molecular Biology and Molecular Medicine. Kluwer Academic
4. Cold spring harbor symposia on quantitative biology Vol. LXXI. 2006. Regulatory RNAs Cold Spring Harbor Laboratory Academic Press
5. Alberts, et al. 2002. Molecular Biology of the Cell, 4th edition.

Teaching Aids & Teacher's Website

https://web2-sso.nchu.edu.tw/pweb/index2.php?pid=530

Office Hours

Friday 10:00-11:00

Sustainable Development Goals, SDGs(Link URL)

include experience courses：N

Please respect the intellectual property rights and use the materials legally.Please respect gender equality.
Update Date, year/month/day：None	Printed Date, year/month/day：2026 / 6 / 19
The second-hand book website：http://www.myub.com.tw/