Relevance of Course Objectives and Core Learning Outcomes(%) |
Teaching and Assessment Methods for Course Objectives |
Course Objectives |
Competency Indicators |
Ratio(%) |
Teaching Methods |
Assessment Methods |
1.瞭解蛋白質結晶的基本原理To understand the basic principles of protein crystallography
2.瞭解如何收集並處理X光繞射數據To understand how to collect and process X-ray diffraction data
3.瞭解如何建立蛋白質的3D立體結構To understand how to build three-dimensional structure of protein
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topic Discussion/Production |
Discussion |
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Course Content and Homework/Schedule/Tests Schedule |
Week |
Course Content |
Week 1 |
介紹重組蛋白質技術 Introduction of Recombinant Protein Production |
Week 2 |
介紹不同的蛋白質表達系統_大腸桿菌及酵母菌系統 Introduction of E. coli and Yeast Expression Systems |
Week 3 |
介紹不同的蛋白質表達系統_昆蟲細胞及哺乳細胞 Introduction of Insect Cell and Mammalian Cell Expression Systems |
Week 4 |
融合蛋白技術 Fusion Protein Techniques |
Week 5 |
蛋白純化原理介紹 Basic Principles of Protein Purification |
Week 6 |
蛋白質純化技術與策略(一) Techniques and Strategies of Protein Purification |
Week 7 |
蛋白質純化技術與策略(二) Techniques and Strategies of Protein Purification |
Week 8 |
蛋白質純化技術與策略(三) Techniques and Strategies of Protein Purification |
Week 9 |
期中測驗 Mid-Term Exam |
Week 10 |
蛋白質晶體學概論 Introduction of Protein Crystallography |
Week 11 |
晶體對稱性 Crystal Symmetry |
Week 12 |
蛋白結晶原理 Protein Crystallization Experiments |
Week 13 |
蛋白結晶實驗 Protein Crystallization Experiments |
Week 14 |
X光繞射學 X-Ray Diffraction |
Week 15 |
相位角解析技術_分子取代法 Phasing Methods_Molecular Replacement |
Week 16 |
自主練習 autonomic learning |
Week 17 |
自主練習 autonomic learning |
Week 18 |
期末測驗 |
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Evaluation |
期中、期末筆試,出席狀況,課堂參與表現 |
Textbook & other References |
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Teaching Aids & Teacher's Website |
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Office Hours |
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Sustainable Development Goals, SDGs |
07.Affordable and Clean Energy   14.Life Below Water   15.Life On Land   17.Partnerships for the Goals | include experience courses:N |
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