週次 |
授課內容 |
第1週 |
1.Locomotion of cells on solid substrates: Lamellipodia and Filopodia
2.The intracellular organization of focal adhesions, podosomes and invadopodia
|
第2週 |
3.Properties of podosomes and invadopodia |
第3週 |
4.Matrix-degrading proteinases at podosomes and invadopodia |
第4週 |
5.A model for the cooperative function of invadopodia and podosomes in tumor invasion |
第5週 |
6.Use of expression arrays to predict disease progression
7.Genetic similarity between primary tumors and derived metastases
|
第6週 |
8.Gene expression patterns and metastatic tropism |
第7週 |
9.Angiogenesis and Lymphangiogenesis: Networks of lymphatic vessels and capillaries |
第8週 |
10.Accelerated angiogenesis: Physiological response and Pathological conditions |
第9週 |
11.Tumor-associated capillaries with more chaotic organization and larger diameter
12.The phases of angiogenesis |
第10週 |
13.Capillary leakiness and deposition of fibrin bundles in the tumor-associated stroma |
第11週 |
14.Influence of hypoxia on angiogenesis |
第12週 |
15.Regulation of angiogenesis |
第13週 |
16.Activators and inhibitors of angiogenesis
17.Angiogenic switch and recruitment of inflammatory cells |
第14週 |
18.The program of wound healing |
第15週 |
19.A variety of distinct cell types in the stroma of carcinomas |
第16週 |
20.Metastasis and dependence on stroma
21.Recruitment of endothelial precursor cells by mammary CAFs |
第17週 |
22.Macrophages represent important participants in activating the tumor-associated stroma
23.Inflammation and Cancer |
第18週 |
24.Nm23 metastasis suppressor: the first metastasis suppressor
25.Regulation of cancer metastasis by stress pathways |