週次 |
授課內容 |
第1週 |
Locomotion of cells on solid substrates: Lamellipodia and Filopodia |
第2週 |
The intracellular organization of focal adhesions, podosomes and invadopodia |
第3週 |
Properties of podosomes and invadopodia |
第4週 |
Matrix-degrading proteinases at podosomes and invadopodia |
第5週 |
A model for the cooperative function of invadopodia and podosomes in tumor invasion |
第6週 |
Genetic similarity between primary tumors and derived metastases |
第7週 |
Gene expression patterns and metastatic tropism |
第8週 |
Angiogenesis and Lymphangiogenesis: Networks of lymphatic vessels and capillaries |
第9週 |
Tumor-associated capillaries with more chaotic organization and larger diameter |
第10週 |
The phases of angiogenesis |
第11週 |
Capillary leakiness and deposition of fibrin bundles in the tumor-associated stroma |
第12週 |
Influence of hypoxia on angiogenesis |
第13週 |
Regulation of angiogenesis |
第14週 |
Activators and inhibitors of angiogenesis |
第15週 |
Angiogenic switch and recruitment of inflammatory cells |
第16週 |
A variety of distinct cell types in the stroma of carcinomas |
第17週 |
Metastasis and dependence on stroma |
第18週 |
Recruitment of endothelial precursor cells by mammary CAFs |