| 國立中興大學教學大綱 |
| 課程名稱 | (中) 維生素與單碳代謝導論(5214) | ||||||||
| (Eng.) Introduction of Vitamins in One Carbon Metabolism | |||||||||
| 開課單位 | 食生碩 | ||||||||
| 課程類別 | 選修 | 學分 | 2 | 授課教師 | 蔣恩沛 | ||||
| 選課單位 | 食生系 / 學士班 | 授課使用語言 | 英文 | 開課學期 | 1151 | ||||
| 課程簡述 | This graduate-level course introduces the roles of vitamins and micronutrients in one-carbon metabolism and their connections to cellular metabolism, metabolic regulation, health, disease, and nutritional intervention. Beyond fundamental knowledge, the course emphasizes a research-oriented and application-driven approach. Students will learn how to formulate research questions, critically evaluate scientific literature, identify appropriate analytical and experimental approaches, and interpret metabolic data. Particular emphasis will be placed on metabolomics, mass spectrometry, stable-isotope metabolic flux tracing, metabolic pathway analysis, and data quality control. Students are encouraged to apply the concepts and tools learned in the course to their own research questions and experimental data. The course follows the principle of: Learn → Apply → Create Rather than completing a conventional term report solely for course assessment, students will develop research-oriented outputs that may contribute to a conference presentation, research proposal, manuscript, patent, or technology-transfer opportunity. Students are expected to have basic knowledge in human physiology and/or nutrition and biochemistry. The following courses are recommended: Human Physiology Nutrition / Nutritional Biochemistry Mass Spectrometry Students with research experience in biochemistry, metabolism, metabolomics, molecular biology, or related fields are also encouraged to enroll. Note: Mass spectrometry is highly recommended because several course topics involve metabolomics and mass-spectrometry-based metabolic analysis. |
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| 先修課程名稱 | |||||||||
| 課程與核心能力關聯配比(%) | 課程目標之教學方法與評量方法 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 課程目標 | 核心能力 | 配比(%) | 教學方法 | 評量方法 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| By the end of the course, students should be able to: Explain the biochemical and physiological roles of vitamins and cofactors in one-carbon metabolism and related metabolic pathways. Integrate vitamin metabolism with broader metabolic networks, including amino acid metabolism, methyl-group metabolism, nucleotide synthesis, redox metabolism, and energy metabolism. Read and critically evaluate current scientific literature and identify important research questions and knowledge gaps. Understand and apply major research approaches used in metabolic research, including metabolomics, mass spectrometry, and stable-isotope metabolic flux tracing. Evaluate experimental data quality, including experimental design, controls, standards, QC procedures, database organization, and data interpretation. Identify and troubleshoot potential problems in metabolic experiments and analytical workflows. Apply course concepts to their own research, experimental data, or research questions. Communicate and develop research outcomes through scientific discussion, data presentation, and research-oriented projects. Develop the ability to transform scientific knowledge and analytical technologies into innovative research value and potential applications. |
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| 授課內容(單元名稱與內容、習作/每週授課、考試進度-共16週加自主學習) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 學習評量方式 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 1. Attend a conference and deliver an oral presentation 2. Written report could be: either a poster (in a real conference/competition), a grant proposal, a manuscript for submission, a patent application (or a term-paper) 3. Class participation and discussions |
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| 教科書＆參考書目(書名、作者、書局、代理商、說明) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Handbook of Vitamins ISBN: 0-8247-0428-2, Third Edition (Clinical Nutrition in Health and Disease) by Robert B. Rucker (Author), John W. Suttie (Author), Donald B. McCormick (Author) Advanced Nutrition and Human Metabolism. 5th ed. Seattle, WA. Nutritional biochemistry by Tom Brody. 2nd. Ed Selected recent papers from the field. |
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| 課程教材（教師個人網址請列在本校內之網址） | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Course materials Lecture printouts. Food and Nutrition in Translational Medicine Workshop from Stover PJ |
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| 課程輔導時間 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| by appointment (另與教師個別約時間) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 請尊重智慧財產權及性別平等意識，不得非法影印他人著作及受保護的電子檔案。 | |
| 更新日期 西元年/月/日：2026/09/15 11:54:03 | 列印日期 西元年/月/日：2026 / 10 / 03 |
| MyTB教科書訂購平台：http://www.mytb.com.tw/ | |