國立中興大學教學大綱
課程名稱 (中) 天然物健康效益特論(6819)
(Eng.) Special Topics in Health Effects of Natural Products
開課單位 代謝碩士學程
課程類別 選修 學分 2 授課教師 顏佩翎
選課單位 代謝碩士學程 / 碩士班 授課使用語言 中/英文 開課學期 1151
課程簡述 This course focuses on exploring the health-promoting effects of natural products through the use of model organisms and advanced omics technologies. Using Caenorhabditis elegans as a primary disease model, students will investigate biological responses to natural compounds in the context of aging, neurodegeneration, metabolic disorders, and gut health. The course covers fundamental techniques for genetic and molecular manipulation, and introduces transcriptomics, metabolomics, and proteomics as tools for functional assessment. By integrating practical lab sessions with data analysis, students will gain a systems-level understanding of how natural products exert their effects, with relevance to drug discovery, functional food development, and sustainable biomedicine.
先修課程名稱
課程與核心能力關聯配比(%) 課程目標之教學方法與評量方法
課程目標 核心能力 配比(%) 教學方法 評量方法
1. To cultivate students’ ability to evaluate the health effects of natural products.
2. To develop students’ capacity to integrate multi-level evidence in assessing the health impacts of natural products.
3. To enhance students’ critical thinking skills in bioactivity and toxicological evaluation.
討論
講授
書面報告
口頭報告
作業
授課內容(單元名稱與內容、習作/每週授課、考試進度-共16週加自主學習)
週次 授課內容
第1週 Course Introduction: Natural Products and Model Organisms in Disease Research
第2週 Overview of C. elegans Genetics and Molecular Tools
第3週 Aging and Longevity Mechanisms
第4週 Lab Demo: Biomarkers for Aging
第5週 Neurodegeneration Model I: Alzheimer’s Models
第6週 Neurodegeneration Model II: Parkinson’s Models
第7週 Lab Demo: Neurodegenerative Strains and Imaging
第8週 Midterm: Journal Presentation on Disease Study
第9週 Metabolic Models: Fat Storage, Obesity, Insulin Signaling
第10週 Host–Pathogen Interaction and Gut Health
第11週 Introduction to Omics Platforms: Transcriptomics, Metabolomics, Proteomics
第12週 Transcriptomics Data: Experimental Design and Analysis
第13週 Applications of Metabolomics in Natural Product Research
第14週 Proteomics Technologies and Applications
第15週 Classical Multi-omics Integration
第16週 Final Project Presentations
自主學習
內容		    03.製作專題報告
This course guides students to actively explore recent research advances and scientific evidence regarding the health effects of natural products. Students are required to independently search for and critically review recent academic literature, review articles, and relevant multimedia resources based on assigned topics, in order to understand the current state of research on the health effects of different natural products.
學習評量方式
Midterm Journal Presentation: 40%;
Laboratory participation: 20%;
Final Project Presentations: 40%.
教科書＆參考書目(書名、作者、書局、代理商、說明)
Hasin Y, Seldin M, Lusis A. Multi-omics Approaches to Disease. Genome Biol. 2017 May 5;18(1):83. doi: 10.1186/s13059-017-1215-1.
WormBook: The Online Review of C. elegans Biology. http://www.wormbook.org
課程教材（教師個人網址請列在本校內之網址）
Lecture slides and selected research articles
課程輔導時間
After class
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更新日期 西元年/月/日：2026/08/20 23:03:54 列印日期 西元年/月/日：2026 / 8 / 25
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