國立中興大學教學大綱
課程名稱 (中) 老化及老化相關疾病特論(5139)
(Eng.) Ageing and Ageing-Associated Diseases
開課單位 生科系
課程類別 選修 學分 2 授課教師 林之儀
選課單位 生命碩士班 / 碩士班 授課使用語言 英文 英文/EMI Y 開課學期 1132
課程簡述 The course aims to equip students with a thorough comprehension of ageing, specifically the molecular-level changes that underlie age-related diseases. By the end of the course, students will have a comprehensive understanding of ageing biology, the hallmarks of ageing, and the molecular changes that drive age-related diseases. They will also be familiar with current research progress in the field and the potential interventions and treatments available.
先修課程名稱
課程含自主學習 Y
課程與核心能力關聯配比(%) 課程目標之教學方法與評量方法
課程目標 核心能力 配比(%) 教學方法 評量方法
Provide students with an understanding of ageing biology and the dynamic changes that contribute to age-related diseases at the molecular level.
8.(丙組)了解生物分子的功能和調節作用
9.(丙組)追求最新生物學發展的熱誠
50
50
討論
講授
口頭報告
其他
書面報告
授課內容(單元名稱與內容、習作/每週授課、考試進度-共18週)
週次 授課內容
第1週 What is ageing?
第2週 2/28 Peace Memorial Day
第3週 Evolution theories of ageing
第4週 Genomic instability in ageing
第5週 The role of telomere in ageing
第6週 Epigenetics of longevity and ageing
第7週 Mitochondrial dysfunction and dysregulated proteostasis
4/4 Tomb Sweeping Festival
第8週 Cellular ageing
第9週 Immunosenescence
第10週 Senotherapeutics
第11週 Neurodegenerative diseases: AD, PD
第12週 Neurodegenerative diseases: HD, ALS
第13週 Cardiovascular diseases
Hematopoietic stem cells: CHIP
第14週 Ageing and respiratory diseases: COPD & IPF
Human premature ageing
第15週 5/30 Adjusted holiday for Dragon Boat Festival holiday
第16週 Endocrine diseases: Type 2 Diabetes Mellitus, Osteoporosis & Hyperparathyroidism, Andropause & Menopause
第17週 Self-directed learning
第18週 Self-directed learning
學習評量方式
Oral presentation: 50%; Writing presentation: 30%; Class engagement: 20%
教科書&參考書目(書名、作者、書局、代理商、說明)
1. Fang, E. F.; Bergersen, L. H.; Gilmour, B. C. Molecular, Cellular, and Metabolic Fundaments of Human Aging; Academic Press: London, UK.
2. Yamada H, Yuji N, editors. Anti-Aging Medicine: Basics and Clinical Practice [Internet]. Singapore: Springer Nature Singapore; 2024 [cited 2025 Feb 14]. Available from: https://link.springer.com/10.1007/978-981-97-8514-8
3. Bennett G. Senotherapy: A Potential Pharmacological Strategy for Prolonging Human Lifespan and Healthspan [Internet]. Singapore: Springer Nature Singapore; 2024 [cited 2025 Feb 14]. (SpringerBriefs in Modern Perspectives on Disability Research). Available from: https://link.springer.com/10.1007/978-981-97-3637-9

Selected papers from high-profile journals.
課程教材(教師個人網址請列在本校內之網址)
ilearning
課程輔導時間
Appointment
聯合國全球永續發展目標(連結網址)
03.健康與福祉提供體驗課程:N
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更新日期 西元年/月/日:2025/02/14 13:12:52 列印日期 西元年/月/日:2025 / 3 / 12
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