國立中興大學教學大綱
課程名稱 (中) 微尺度操控技術(6735)
(Eng.) Manipulation of micro-scale objects using microfluidics
開課單位 機械系
課程類別 選修 學分 3 授課教師 蔣雅郁
選課單位 機械系 / 碩士班 授課使用語言 中文 開課學期 1081
課程簡述 ★選修本課程之同學,必須先參與暑期先修課程,確保具有先期知識與技術;未修習暑期先修課程者,請勿選課。★

課程包含介紹進階微製程技術、微觀流體的設計與相關應用領域,如:細胞操控、化合物分析、生醫檢測等等。課程除一般1)課堂講授之外,另有2)分析工具製作的實驗課,並依照條件設與規劃一微流體元件或完成流場可視化觀察、模擬與分析,3)學生亦必須閱讀至少四篇國際論文,簡報其內容後,進行優劣分析。

This is an advance course on microdevice/microfluidics at the senior undergraduate and post-graduate level. Summer training program is required before attending this advance course.

It covers advance micro-scale flows and microfabrication. The fundamentals of fluid flows at micro-scale including intermolecular forces, low Re flows, slip theory, capillary flows and electrokinetics are discussed. The principles of microfabrication with silicon and polymer substrates are illustrated. Theory and design of various microfluidic components including micropumps, micromixers, microvalves etc is discussed. Few applications of microfluidic systems are also covered. The course also includes design of microfluidic components and few applications of microfluidic systems. A device design project and analysis are applied to students.
先修課程名稱
課程與核心能力關聯配比(%) 課程目標之教學方法與評量方法
課程目標 核心能力 配比(%) 教學方法 評量方法
學習微尺度下流體各項特性與相關學術與產業應用與團隊實作。
Understanding the microfluidics, a multidisciplinary field involving the behaviour of fluids at the microscale, the control of small volumes of fluids (typically meaning ul, nl, pl or fl) and the design of systems that handle these small volumes. Students will be explore the different strategies which microfluidics provided to study the behaviour of rare or single cells and the potential application.
1.具備機械領域之專業知識與獨立解決問題之能力。
2.具備創新思考、規劃並執行研究專題及表達研究成果之能力。
3.具協調跨領域人才與整合技術之能力。
4.具良好的產業國際觀。
5.具領導、管理、規劃及自我學習成長之能力。
40
30
10
10
10
專題探討/製作
討論
實習
講授
參訪
書面報告
出席狀況
口頭報告
實作
作品
作業
測驗
授課內容(單元名稱與內容、習作/每週授課、考試進度-共18週)
週次(week) 課程單元或主題
(subject and content)

A
• Course Introduction
• Introduction to “Paper Review” (SWOT)
• Introduction to “Design Project”
• Maker Microscope


B Physics of Fluids

1 Unidirectional flow
2 Navier-Stokes equation of motion
 2.1 steady pressure
  2.1.1 couette flow
  2.1.2 poiseuille flow
3 Bernoulli's principle
4 Hydraulic Circuit Analysis
 4.1 Hydraulic circuit equivalents for fluid flow in microchannels


C Moon Festival


D Physics of Fluids II

5 Transport in microfluidics
 5.1 Intoduce Re and Pe
 5.2 Fick's Law
 5.3 Mixing in microfluidics
  5.3.1 passive
  5.3.2 active


E Technique in microfluidics

6 Manipulation Technique in microfluidics
 6.1 Passive
 6.2 Active


F Two phase flow


G Microfabrication Technology
•  Clean room
•  Polymer

H Lab tour / scientific instrument practicum


I Midterm


J Fabrication practicum


K Experiment in Lab I


L Paper Review present I


M Paper Review present II


N Next stage of microfluidics


O Experiment in Lab II


P Experiment in Lab III


Q Design project present I


R Design project present II and feedback


學習評量方式
暑期先修課程:30% (需完成基本機台訓練與考核)
期中考:30%
報告:30%
出席:10%
教科書&參考書目(書名、作者、書局、代理商、說明)
教科書
There is no standard textbook. We will use a combination of lecture notes generated from several textbooks and recent research articles. Notes will be distributed during class, and placed on the course website.
課程教材(教師個人網址請列在本校內之網址)
本課程除傳統課堂教授外,首次引入微流控與其光學分析工具之製作的實作課程。預估使用軟體、加工與分析機台如下,請參與暑期先修多物理模擬課程如COMSOL或Anysis,以利完成報告:

設計:使用免費軟體openSCAD與Draftsight
加工機台:雷射切割機、熱壓機、光固化3D列表機、桌上型CNC
分析機台:高速攝影機、顯微鏡、針筒式幫浦
模擬:COMSOL
課程輔導時間
Arrange it directly with teacher.
聯合國全球永續發展目標(連結網址)
 提供體驗課程:N
請尊重智慧財產權及性別平等意識,不得非法影印他人著作。
更新日期 西元年/月/日:無 列印日期 西元年/月/日:2026 / 4 / 11
MyTB教科書訂購平台:http://www.mytb.com.tw/