國立中興大學教學大綱
課程名稱 (中) 動物病毒學文獻探討(一)(6292)
(Eng.) Seminar on Animal Virology (I)
開課單位 獸醫系
課程類別 選修 學分 1 授課教師 王之仰 等
選課單位 獸病所 / 碩士班 授課使用語言 中/英文 英文/EMI 開課學期 1141
課程簡述 This class is to design as the journal club for the graduate students who are interested to acquire some advanced knowledge in the field of molecular microbiology and molecular virology.
Students can learn how to design, interpret, and complete a scientific research proposal after reading papers.
先修課程名稱
課程含自主學習 Y
課程與核心能力關聯配比(%) 課程目標之教學方法與評量方法
課程目標 核心能力 配比(%) 教學方法 評量方法
1.Establishment of the basic reading ability for the graduate student.
2.Training of the scientific research capacity for the graduate student.
3.Understanding of the experiment techniques in the molecular virology for the graduate student.
2.獸醫病理學、微生物學及生物醫學之實驗操作技術
3.病理生物醫學訓練、致病機理研究及生技研發技術等關鍵能力的培養
50
50
討論
口頭報告
授課內容(單元名稱與內容、習作/每週授課、考試進度-共16週加自主學習)
週次 授課內容
第1週 Canarypox and fowlpox viruses as recombinant vaccine vectors: a biological and immunological comparison. Antiviral Res. 88:53-63.
第2週 New insight into avian papillomavirus ecology and evolution from characterization of novel wild bird papillomaviruses. Front. Microbiol. 10:701
第3週 Apoptosis triggered by ORF3 proteins of the circoviridae family. Frontiers in cellular and infection microbiology 10:609071
第4週 Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek’s disease virus. J. Virol. 74:3605-3612
第5週 Cell permeabilization by poliovirus 2B viroporin triggers bystander permeabilization in neighbouring cells through a mechanism involving gap junctions. Cell. Microbiol. 12:1144-1157.
第6週 Inhibition of anti-viral stress granule formation by coronavirus endoribonuclease nsp15 ensures efficient replication. PLoS Pathog. 17(2):e1008690
第7週 The herpes simplex virus host shutoff (vhs) RNase limits accumulation of double stranded RNA in infected cells: evidence for accelerated decay of duplex RNA. PLoS Pathog. 15(10):e1008111
第8週 Student report:I
第9週 Characterization, functional and signaling elucidation of pigeon (Columba livia) interferon-gamma: knockdown p53 negatively modulates antiviral response. Dev. Comp. Immunol. 90:29-40
第10週 Recovirus NS1-2 has viroporin activity that induces aberrant cellular calcium signaling to facilitate virus replication. mSphere 4:e00506-19
第11週 Student report:II
第12週 Interferon gamma prevents infectious entry of human papillomavirus 16 via an L2-dependent mechanism. J. Virol. 91:e00168-17
第13週 Encephalomyocarditis virus viroporin 2B activates NLRP3 inflammasome. PLoS Pathog. 8:e1002857
第14週 Student report:III
第15週 Genome-wide classification of type I, type II, and type III interferon-stimulated genes in chicken fibroblasts. Vaccines 7:160
第16週 Recombinant infectious bronchitis coronavirus Beaudette with the spike protein gene of the pathogenic M41 strain remains attenuated but induces protective immunity. Journal of Virology 78:13804-13811 A reporter system for assaying influenza virus RNP functionality based on secreted Gaussia luciferase activity. Virol. J. 8:29 Final discussion
自主學習
內容

學習評量方式
The performance of report and discussion
教科書&參考書目(書名、作者、書局、代理商、說明)
Journal of Virology
Journal of General Virology
Virology
Veterinary Virology
Plos One
Vaccine
課程教材(教師個人網址請列在本校內之網址)

課程輔導時間
Friday 4:00 PM-5:00 PM
聯合國全球永續發展目標(連結網址)
 提供體驗課程:N
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更新日期 西元年/月/日:無 列印日期 西元年/月/日:2025 / 9 / 01
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