NCHU Course Outline
Course Name (中) 大腦可塑性與神經元新生特論(5137)
(Eng.) Special Topics of Neuroplasticity and Neurogenesis
Offering Dept Department of Life Sciences
Course Type Elective Credits 2 Teacher Yu-Wen Hung
Department Department of Life Sciences / Graduate Language Chinese 英文/EMI Semester 2025-SPRING
Course Description This course will address current knowledge of the difference and relation between neuroplasticity and neurogenesis and how they affect the brain. The processes and molecular mechanisms of neuroplasticity and neurogenesis in immature and adult brain as well as brain disorder would be introduced.
Prerequisites
self-directed learning in the course Y
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
After completion of this course, students will 1) know the current theories accounting for the neuroplasticity and neurogenesis, and 2) gain a comprehensive understanding of the ability to make adaptive changes related to the structure and function of the nervous system from molecules to networks.
6.Realizing the development and regulatory mechanisms of the organisms
100
Discussion
Lecturing
Written Presentation
Attendance
Oral Presentation
Quiz
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 Course introduction

Week 2 Introduction to synaptic circuits
Week 3 Membrane properties and neurotransmitter actions
Week 4 Wiring the brain
Week 5 Glutamate-mediated neuroplasticity
Week 6 Long-term potentiation and synaptogenesis
Week 7 Holiday
Week 8 Neuroplasticity, learning and memory
Week 9 Paper presentation
Week 10 Paper presentation
Week 11 Basic Aspects of Neurogenesis
Week 12 Fate Specification of Neural Stem Cells
Week 13 Neurogenesis during development
Week 14 Neurogenesis in adult brain
Week 15 Integration of new neurons into the adult hippocampus
Week 16 Adult neurogenesis: Beyond learning and memory
Week 17 Self-directed learning (Review of course content and write a brief report)
Week 18 Self-directed learning (Review of course content and write a brief report)
Evaluation
Paper presentation (40%)
Homework (40%)
Course participation (20%)
Textbook & other References
-The synaptic organization of the brain / edited by Gordon M.Shepherd
-Neuroplasticity: new biochemical mechanisms / edited by J. A. Costa e Silva, J. P. Macher, J. P. Olie
-Neurogenesis in the adult brain I: neurobiology / edited by Tatsunori Seki, Kazunobu Sawamoto, Jack M. Parent and Arturo Alvarez-Buylla
-Neurogenesis research: new developments / edited by Gerry J. Clark and Walcot T. Anderson
Neuroscience: exploring the brain 4th Edition/ edited by Mark F. Bear, Barry W. Connors, Michael A. Paradiso
Principles of neural science 6th Edition/ edited by Eric R. Kandel, James H. Schwartz, and Thomas M. Jessell
Most recent 5-year research and review articles in the neuroscience field
Teaching Aids & Teacher's Website
iLearning
Office Hours
與授課教師預約
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Update Date, year/month/day:2025/02/26 18:44:36 Printed Date, year/month/day:2025 / 5 / 09
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