國立中興大學教學大綱
課程名稱 (中) 幹細胞生物學(8074)
(Eng.) Stem Cell Biology
開課單位 組醫學程
課程類別 選修 學分 3 授課教師 蘇鴻麟
選課單位 組醫學程 / 博士班 授課使用語言 中文 英文/EMI N 開課學期 1051
課程簡述 本課程介紹各式幹細胞的研究與應用,包括胚胎幹細胞及體幹細胞例如造血、間葉、生殖、神經、表皮、心臟、角膜、肝臟及胰臟等組織幹細胞,同時本課程也將說明什麼是腫瘤幹細胞。本課程將透過基礎觀念的建立與了解,循序漸進介紹細胞生長調節、幹細胞研究方法、幹細胞分化以及組織發育機制,同時配合指定文獻的閱讀與報告中,以建立學生對幹細胞研究思考判斷的能力。
The Stem Cell Biology Course is primarily consisted of a series of lectures which covers from basics of the general biology of stem cells to a more in-depth discussion on various stem cell types: embryonic stem cells, adult somatic stem cells and cancer stem cells, and finally to some of their potential clinical application/implication. For evaluation, students are required to write a review essay on designated research topics so that they can horn their skills in the search, organization and
critical assessment of literatures.
先修課程名稱
課程含自主學習 N
課程與核心能力關聯配比(%) 課程目標之教學方法與評量方法
課程目標 核心能力 配比(%) 教學方法 評量方法
了解幹細胞的基礎知識與臨床應用。
網路/遠距教學
其他
講授
書面報告
出席狀況
口頭報告
授課內容(單元名稱與內容、習作/每週授課、考試進度-共18週)
09/22 Dr. Hong-Lin Su (蘇鴻麟)
09/29 Key determinants of stem cell fate and stem cell niche Dr. Jean Lu (呂仁) GRC/AS
10/06Introduction of stem cell biology Dr. Chia-Ning Shen (沈家寧) GRC/AS
Ethical issues in stem cell research Dr. Thai-Yen Lin (林泰元) NTU
10/13 Embryonic stem cells & induced pluripotency Dr. Hung-Chih Kuo (郭紘志) ICOB/AS
10/20 Epigenetic controls of cell fate Dr. Li-Jung Juan (阮麗蓉) GRC/AS
10/27 Molecular genetics and development of mouse Dr. Yu-Ting Yan (顏裕庭) IBMS/AS
11/03 Interrogating neural development by stem cells Dr. Jun-An Chen (陳俊安) IMB/AS
Niche Regulation in Germ Cell Pluripotency and Somatic Cancer Dr. Yen-Hua Huang (黃彥華) TMU
11/10 Expansion & differentiation of hematopoietic stem cells Dr. Chao-Ling Yao (姚少凌) YZU
Hematopoietic stem cells and their fate determination Dr. Po-Min Chiang (江伯敏) NCKU
11/17 Mechanisms & Application of Mesenchymal Stem Cell Immunomodulation Dr. Betty Yen (顏伶汝) NHRI
Clinical use of mesenchymal stem cells Dr. Jennifer Ho (何慧君) TMU
11/24 Derivation of ES cells from somatic cell nuclear transfer Dr. Li-Ying Sung (宋麗英) NTU
Stem cell therapy for neurodegenerative diseases Dr. Hong-Lin Su (蘇鴻麟) NCHU
12/01 Stem cells in digestive system Dr. Chia-Ning Shen (沈家寧) GRC /AS
12/08 Bioengineering for hair follicle regeneration Dr. Sung-Jan Lin (林頌然) NTU
Limbal stem cell for ocular surface reconstruction Dr. Ray Tsai (蔡瑞芳) TMU
12/15 Stem cell therapy for cardiac regeneration Dr. Patrick Hsieh (謝清河) IBMS/AS
12/22 Cancer stem cells and cancer metastasis Dr. Muh-Hwa Yang (楊慕華) NYMU
12/29 Hypoxia, mesenchymal stem cells & cancer Dr. Shih-Chieh Hung (洪士杰) NYMU
01/05 Phage display technique to search for stem cell markers Dr. Han-Chung Wu (吳漢忠) ICOB
Stem cell manipulation in GTP/GMP facilities Dr. Peter Pang (馮清榮) TCU
01/12 Student Presentation Drs Patrick Hsieh, Jean Lu, HC Kuo & CN Shen AS
學習評量方式
(i) A written essay on a selected topics 40 %
(ii) A short presentation on a selected topics (10 min) 40%
(ii) Attendance 20 %
教科書&參考書目(書名、作者、書局、代理商、說明)

課程教材(教師個人網址請列在本校內之網址)

課程輔導時間
星期四13:00-15:00
聯合國全球永續發展目標(連結網址)
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更新日期 西元年/月/日:無 列印日期 西元年/月/日:2025 / 7 / 04
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