NCHU Course Outline
Course Name (中) 基礎毒理學(3250)
(Eng.) Basic Toxicology
Offering Dept Department of Food Science and Biotechnology
Course Type Elective Credits 2 Teacher CHEN, YNG-TAY
Department Department of Food Science and Biotechnology / Undergraduate Language Chinese Semester 2026-SPRING
Course Description (中文) 本基礎毒理學課程主要著重食品中可能危害物質對生物體作用之探討,包括研究對生物體之毒性作用機制。本課程將討論食品中潛在毒性物質暴露引起生物體內反應及危害之可能作用機制,並介紹新興食品安全性與功效性評估。
(English) This foundational toxicology course mainly focuses on the discussion of the effects of potentially hazardous substances in food on organisms, including the study of the mechanism of toxic effects on organisms. This course will discuss the possible mechanism of action of in vivo reactions and hazards caused by exposure to potentially toxic substances in food, and introduce emerging food safety and efficacy assessments.
Prerequisites
Relevance of Course Objectives and Core Learning Outcomes(%) Teaching and Assessment Methods for Course Objectives
Course Objectives Competency Indicators Ratio(%) Teaching Methods Assessment Methods
(中文) 使學生瞭解毒物對生物體危害相關知識,培養具有食品安全知識的人才。
(英文) The aim of toxicology is to introduce and understand the various toxicant effects and train the concepts in food safety.
Discussion
Lecturing
Attendance
Quiz
Course Content and Homework/Schedule/Tests Schedule
Week Course Content
Week 1 毒理學的歷史
History of Toxicology
Week 2 食品中毒事件導讀
Introduction to important food intoxication incidents
Week 3 中毒與解毒的機制
The mechanism of intoxication and detoxification
Week 4 毒物生物轉化作用
Biotransformation of xenobiotics
Week 5 食品的毒性與安全
Food Toxicity and Safety
Week 6 我們所暴露的食品有哪些毒性?
What are the toxicities of the foods we are exposed to?
Week 7 暴露多少量會中毒?
How much exposure would be toxic?
Week 8 期中考
Midterm exam
Week 9 食品中毒後的代謝
Metabolism after food poisoning
Week 10 基因毒性
Genetic toxicity
Week 11 肝臟及腎臟毒理
Toxic responses of the liver and kidney
Week 12 食品及添加物毒性
Food and additive toxicology
Week 13 動物性食品中的天然毒素
Natural toxins in animal foodstuffs
Week 14 新興食品安全性測試方法
Emerging food safety test methods
Week 15 毒性風險評估
Risk assessment
Week 16 期末考
Final exam 自主學習:替代毒理試驗線上課程I 自主學習:替代毒理試驗線上課程II
self-directed
learning

Evaluation
測驗、出席狀況。
Textbook & other References
1.Hayes’ Principles and Methods of Toxicology, Sixth Edition 6th Edition, by A. Wallace Hayes (Editor), Claire L. Kruger (Editor) 2014
2.Principles and Methods of Toxicology, Fifth Edition 5th Edition by A. Wallace Hayes (Editor) 2007
3.Casarett & Doull’s Toxicology: The Basic Science of Poisons, Eighth Edition by Curtis Klaassen 2013
4.Casarett & Doull’s Essentials of Toxicology, Third Edition (Lange) by Curtis Klaassen 2015
Teaching Aids & Teacher's Website
iLearning
Office Hours
週四5,6節
Sustainable Development Goals, SDGs(Link URL)
include experience courses:N
Please respect the intellectual property rights and use the materials legally.Please respect gender equality.
Update Date, year/month/day:None Printed Date, year/month/day:2026 / 6 / 27
The second-hand book website:http://www.myub.com.tw/